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NCT00843531 · ClinicalTrials.gov registry record · Phase 2

RAD001 and Erlotinib in Patients With Neuroendocrine Tumors

A Phase 2 study, sponsored by University of California, San Francisco.

Terminated
Registry status
Phase 2
Development phase
17
Enrollment target

NCT00843531: Clinical Trial Phase 2 study, sponsored by University of California, San Francisco.

NCT00843531 is a Phase 2 study that was terminated before completion, run by University of California, San Francisco. The registered enrollment target is 17 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00843531, a Phase 2 study, was terminated before completion, sponsored by University of California, San Francisco.

TERMINATED
Registry status
Phase 2
Development phase
17 participants
Enrollment target

Study Summary

The purpose of this study is to test how safe and effective the combination of RAD001 and erlotinib is in patients with neuroendocrine tumors.

Primary Outcome

Objective response is defined as complete response (CR) or partial response (PR) assessed using Response Evaluation Criteria in Solid Tumors (RECIST) criteria. The primary analysis population is based on efficacy-evaluable patients, defined as those patients who receive at least one cycle of RAD001 plus erlotinib and undergo at least one post-baseline response assessment or die while on therapy.

Interventions

  • DRUG RAD001
  • DRUG erlotinib

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2009-06-25
Est. Completion 2016-08-20
Phase Phase 2

Why NCT00843531 stopped before completion

NCT00843531 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (87% lower).

The record links to 0 conditions, and to 2 interventions - of which RAD001 is the first listed.

NCT00843531 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00843531 about?

NCT00843531 is a clinical study titled "RAD001 and Erlotinib in Patients With Neuroendocrine Tumors". The purpose of this study is to test how safe and effective the combination of RAD001 and erlotinib is in patients with neuroendocrine tumors.

What is the current status of trial NCT00843531?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 17 participants. The study started on 2009-06-25. Estimated completion is 2016-08-20.

What interventions are being tested in trial NCT00843531?

The interventions under investigation include: RAD001 (DRUG), erlotinib (DRUG).

Who is sponsoring clinical trial NCT00843531?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00843531's enrollment target sits among peer trials

17 1903rd of 2000 higher than 93 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00843531, the US trial registry maintained by the National Library of Medicine. NCT00843531 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.