Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00842023 · ClinicalTrials.gov registry record · Phase 4

Assessment of Biomarkers and Cardiorenal Syndrome in Acute Decompensated Heart Failure With Vasodilator Therapy

A Phase 4 study, sponsored by Western University of Health Sciences.

Completed
Registry status
Phase 4
Development phase
89
Enrollment target

NCT00842023: Completed Phase 4 study, sponsored by Western University of Health Sciences.

NCT00842023 is a Phase 4 study that has completed, run by Western University of Health Sciences. The registered enrollment target is 89 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00842023, a Phase 4 study, has completed, sponsored by Western University of Health Sciences.

COMPLETED
Registry status
Phase 4
Development phase
89 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether Nesiritide is more effective than nitroglycerin in modifying inflammatory and neurohormonal biomarkers without renal toxicity when proper infusion duration is administered.

Primary Outcome

Serum creatinine values and changes in serum creatinine

Interventions

  • DRUG Nitroglycerin
  • DRUG Nesiritide

Trial Details

FieldValue
Enrollment Target 89 participants
Start Date 2006-07
Est. Completion 2009-02
Phase Phase 4

What the finished NCT00842023 record still lists

NCT00842023 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 89 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 2 interventions - of which Nitroglycerin is the first listed.

NCT00842023 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00842023 about?

NCT00842023 is a clinical study titled "Assessment of Biomarkers and Cardiorenal Syndrome in Acute Decompensated Heart Failure With Vasodilator Therapy". The purpose of this study is to determine whether Nesiritide is more effective than nitroglycerin in modifying inflammatory and neurohormonal biomarkers without renal toxicity when proper infusion duration is administered.

What is the current status of trial NCT00842023?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 89 participants. The study started on 2006-07. Estimated completion is 2009-02.

What interventions are being tested in trial NCT00842023?

The interventions under investigation include: Nitroglycerin (DRUG), Nesiritide (DRUG).

Who is sponsoring clinical trial NCT00842023?

This trial is sponsored by Western University of Health Sciences, which has 16 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00842023's enrollment target sits among peer trials

89 913th of 2000 higher than 1,085 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03682289 · 89 participants · Phase 2

    Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

  • NCT04787939 · 89 participants · NA

    Early Feeding After Oral Cavity Reconstruction

  • NCT05480449 · 89 participants · Phase 1

    Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)

  • NCT05604131 · 89 participants · Phase 2

    Cardiac MRI-guided Deferiprone Therapy for Acute Myocardial Infarction Patients

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00842023, the US trial registry maintained by the National Library of Medicine. NCT00842023 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.