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NCT00828243 · ClinicalTrials.gov registry record
Genetic Regulation of Surfactant Deficiency
A clinical trial, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- 525
- Enrollment target
NCT00828243: Completed study, sponsored by Washington University School of Medicine.
NCT00828243 is a clinical trial that has completed, run by Washington University School of Medicine. The registered enrollment target is 525 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00828243 has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- 525 participants
- Enrollment target
Study Summary
Inherited deficiencies in any one of 3 genes (surfactant protein B, surfactant protein C, and ATP-binding cassette transporter A3) can cause neonatal respiratory distress syndrome by disrupting metabolism of the pulmonary surfactant. The investigators will use state of the art methods to link specific changes in the genetic code of each of these genes with disruption of discrete steps in the metabolism of the pulmonary surfactant in human newborn infants. These studies will lead to improved diagnostic capabilities and suggest novel strategies to correct surfactant deficiency in newborn infants.
Primary Outcome
Statistical association of increased risk of neonatal respiratory distress in term or near term infants with specific genomic variants in SFTPB, SFTPC, and ABCA3
Interventions
- DRUG Nutrient
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 525 participants |
| Start Date | 2007-11 |
| Est. Completion | 2013-03 |
What the finished NCT00828243 record still lists
NCT00828243 is an observational study that tracks outcomes without assigning an intervention. The registered 525 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Nutrient is the first listed.
NCT00828243 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00828243 about?
NCT00828243 is a clinical study titled "Genetic Regulation of Surfactant Deficiency". Inherited deficiencies in any one of 3 genes (surfactant protein B, surfactant protein C, and ATP-binding cassette transporter A3) can cause neonatal respiratory distress syndrome by disrupting metabolism of the pulmonary surfactant. The investigators will use state of the art methods to link specif...
What is the current status of trial NCT00828243?
This trial is currently completed. The enrollment target is 525 participants. The study started on 2007-11. Estimated completion is 2013-03.
What interventions are being tested in trial NCT00828243?
The interventions under investigation include: Nutrient (DRUG).
Who is sponsoring clinical trial NCT00828243?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
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