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NCT00804713 · ClinicalTrials.gov registry record · NA

Screening for Latent Tuberculosis Infection (LTBI) in US Army Recruits

A NA study, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.

Completed
Registry status
NA
Development phase
2,017
Enrollment target

NCT00804713: Completed NA study, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.

NCT00804713 is a NA study that has completed, run by Henry M. Jackson Foundation for the Advancement of Military Medicine. The registered enrollment target is 2,017 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (44% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00804713, a NA study, has completed, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.

COMPLETED
Registry status
NA
Development phase
2,017 participants
Enrollment target

Study Summary

The overall objective of this study is to assess the feasibility and potential impact of using a targeted testing approach and 2 interferon-gamma release assays (IGRA) to screen for latent tuberculosis (TB) infection (LTBI) among military recruits. The current policy of universal application of the Mantoux tuberculin skin test (TST) to screen for LTBI may result in many TST reactions among recruits who are at low risk for LTBI. The central hypothesis is that targeted testing by use of the questionnaire will reduce unnecessary testing of low-risk recruits without affecting the identification of higher-risk recruits. The secondary hypothesis is that many discordant results between the TST and IGRA may be explained by cross-reactivity to non-tuberculous mycobacteria (NTM) with the TST.

Primary Outcome

Risk stratification and test result. Risk was stratified by the use of risk factors identified by questionnaire according to the 5, 10 and 15 mm criteria (CDC Morbidity and Mortality Weekly Report Recommendations and Reports 2000. Targeted Testing for Latent Tuberculosis Infection.) The number of 1803 is used here because that is the number for which valid results were available for all 4 tests. The number presented in each category is the number of participants that had positive results. We

Interventions

  • DRUG BST
  • DRUG TST
  • OTHER QFT
  • OTHER T-spot

Trial Details

FieldValue
Enrollment Target 2,017 participants
Start Date 2009-03
Est. Completion 2022-08
Phase NA

What the finished NCT00804713 record still lists

NCT00804713 is an interventional study that assigns participants to a tested intervention. Its 2,017 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (44% higher).

The record links to 0 conditions, and to 4 interventions - of which BST is the first listed.

NCT00804713 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00804713 about?

NCT00804713 is a clinical study titled "Screening for Latent Tuberculosis Infection (LTBI) in US Army Recruits". The overall objective of this study is to assess the feasibility and potential impact of using a targeted testing approach and 2 interferon-gamma release assays (IGRA) to screen for latent tuberculosis (TB) infection (LTBI) among military recruits. The current policy of universal application of the ...

What is the current status of trial NCT00804713?

This trial is currently completed. It is a NA study. The enrollment target is 2,017 participants. The study started on 2009-03. Estimated completion is 2022-08.

What interventions are being tested in trial NCT00804713?

The interventions under investigation include: BST (DRUG), TST (DRUG), QFT (OTHER), T-spot (OTHER).

Who is sponsoring clinical trial NCT00804713?

This trial is sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine, which has 60 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00804713's enrollment target sits among peer trials

2,017 52nd of 2000 higher than 1,949 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00804713, the US trial registry maintained by the National Library of Medicine. NCT00804713 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.