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NCT00798252 · ClinicalTrials.gov registry record · Phase 1

Ascending Multiple-Dose Study of Brivanib Alaninate in Combination With Chemotherapeutic Agents in Subjects With Advanced Cancers

A Phase 1 study of Advanced Cancer, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 1
Development phase
111
Enrollment target
5
Study locations

NCT00798252: Completed Phase 1 study of Advanced Cancer, sponsored by Bristol-Myers Squibb.

NCT00798252 is a Phase 1 study of Advanced Cancer that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 111 participants, below the 245-participant average among 122 other Advanced Cancer trials with a reported enrollment target (55% lower). The trial reports 5 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00798252, a Phase 1 study of Advanced Cancer, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 1
Development phase
111 participants
Enrollment target
5
Study locations

Study Summary

To determine safety and maximum tolerated dose of brivanib alaninate when administered in combination with capecitabine, doxorubicin, ixabepilone, docetaxel and paclitaxel chemotherapy to subjects with advanced or metastatic solid tumors

Conditions Studied

Interventions

  • DRUG Docetaxel
  • DRUG Capecitabine
  • DRUG Doxorubicin
  • DRUG Paclitaxel
  • DRUG Ixabepilone

Study Locations (5)

California

  • Usc/Norris Comprehensive Cancer Center - Los Angeles

Massachusetts

  • Dana Farber Cancer Institute - Boston

Michigan

  • Wayne State University - Detroit

Alberta

  • Local Institution - Edmonton

Ontario

  • Local Institution - Toronto

Trial Details

FieldValue
Enrollment Target 111 participants
Start Date 2009-03
Est. Completion 2015-05
Phase Phase 1
Bristol-Myers Squibb

1,025 total trials

What the finished NCT00798252 record still lists

NCT00798252 is an interventional study that assigns participants to a tested intervention. The registered 111 participants enrollment target is mid-sized for trials with a published cap, below the 245-participant average among 122 other Advanced Cancer trials with a reported enrollment target (55% lower).

The record links to 1 condition, with Advanced Cancer appearing as the primary indexed condition, and to 5 interventions - of which Docetaxel is the first listed.

NCT00798252 lists 5 locations in 5 states (California, Massachusetts, Michigan).

Frequently Asked Questions

What is clinical trial NCT00798252 about?

NCT00798252 is a clinical study titled "Ascending Multiple-Dose Study of Brivanib Alaninate in Combination With Chemotherapeutic Agents in Subjects With Advanced Cancers". To determine safety and maximum tolerated dose of brivanib alaninate when administered in combination with capecitabine, doxorubicin, ixabepilone, docetaxel and paclitaxel chemotherapy to subjects with advanced or metastatic solid tumors

What is the current status of trial NCT00798252?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 111 participants. The study started on 2009-03. Estimated completion is 2015-05.

What conditions does trial NCT00798252 study?

This clinical trial studies the following conditions: Advanced Cancer.

What interventions are being tested in trial NCT00798252?

The interventions under investigation include: Docetaxel (DRUG), Capecitabine (DRUG), Doxorubicin (DRUG), Paclitaxel (DRUG), Ixabepilone (DRUG).

Who is sponsoring clinical trial NCT00798252?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00798252 being conducted?

This trial has 5 study locations across California, Massachusetts, Michigan, Alberta, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Advanced Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00798252's enrollment target sits among peer trials

111 56th of 122 higher than 67 of 122 other Advanced Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Advanced Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00798252, the US trial registry maintained by the National Library of Medicine. NCT00798252 (mid enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.