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NCT00795639 · ClinicalTrials.gov registry record · Phase 3

Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)

A Phase 3 study, sponsored by Pfizer.

Terminated
Registry status
Phase 3
Development phase
183
Enrollment target

NCT00795639: Clinical Trial Phase 3 study, sponsored by Pfizer.

NCT00795639 is a Phase 3 study that was terminated before completion, run by Pfizer. The registered enrollment target is 183 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (76% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00795639, a Phase 3 study, was terminated before completion, sponsored by Pfizer.

TERMINATED
Registry status
Phase 3
Development phase
183 participants
Enrollment target

Study Summary

This protocol is for subjects with pulmonary arterial hypertension and is the first of 3 studies forming the Sitaxsentan efficacy and safety trial with Randomized Prospective Assessment of Adding Sildenafil (SR-PAAS) program.

Primary Outcome

6 MWD was the distance that a participant could walk in 6 minutes. Participants were asked to perform the test at a pace that was comfortable to them, with as many breaks as they needed. Continuous pulse oximetry was conducted during the test for safety. Change is Week 12 results minus baseline results.

Interventions

  • DRUG Placebo
  • DRUG Sitaxsentan

Trial Details

FieldValue
Enrollment Target 183 participants
Start Date 2008-12
Est. Completion 2011-03
Phase Phase 3
Pfizer

1,845 total trials

Why NCT00795639 stopped before completion

NCT00795639 is an interventional study that assigns participants to a tested intervention. The registered 183 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (76% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00795639 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00795639 about?

NCT00795639 is a clinical study titled "Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)". This protocol is for subjects with pulmonary arterial hypertension and is the first of 3 studies forming the Sitaxsentan efficacy and safety trial with Randomized Prospective Assessment of Adding Sildenafil (SR-PAAS) program.

What is the current status of trial NCT00795639?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 183 participants. The study started on 2008-12. Estimated completion is 2011-03.

What interventions are being tested in trial NCT00795639?

The interventions under investigation include: Placebo (DRUG), Sitaxsentan (DRUG).

Who is sponsoring clinical trial NCT00795639?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00795639's enrollment target sits among peer trials

183 1420th of 2000 higher than 580 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00795639, the US trial registry maintained by the National Library of Medicine. NCT00795639 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.