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NCT00788866 · ClinicalTrials.gov registry record · NA
Impact of Maternal Pomegranate Juice on Brain Injury in Infants With Intrauterine Growth Restriction (IUGR)
A NA study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 80
- Enrollment target
NCT00788866: Completed NA study, sponsored by Washington University School of Medicine.
NCT00788866 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 80 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00788866, a NA study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
Study Summary
Infants with intrauterine growth restriction are known to be at increased risk for long term neurodevelopmental delay into adulthood. The main mechanism for this is likely decreased blood flow to the brain secondary to altered placental blood flow. Antioxidants may serve to protect the developing brain from this process. Animal studies have shown that pomegranate juice protects the fetal brain from injury in a model of stroke. This clinical trial is intended to evaluate if giving mothers pomegranate juice during the last several weeks of pregnancy can help protect intrauterine growth restricted babies' brains.
Primary Outcome
1. Qualitative MRI injury- white matter injury (WMI) and gray matter injury (GMI) 2. Brain Metrics on MR imaging 3. Diffusion- apparent diffusion coefficient (ADC) and fractional anisotropy (FA) 4. Spectroscopy- lactate and NAA levels in the basal ganglia 5. Advanced MRI development indices - brain volumes, surface based morphology (SBM, folding indices)
Interventions
- DIETARY_SUPPLEMENT Placebo
- DIETARY_SUPPLEMENT Pomegranate Juice
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2008-12 |
| Est. Completion | 2014-10 |
| Phase | NA |
What the finished NCT00788866 record still lists
NCT00788866 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00788866 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00788866 about?
NCT00788866 is a clinical study titled "Impact of Maternal Pomegranate Juice on Brain Injury in Infants With Intrauterine Growth Restriction (IUGR)". Infants with intrauterine growth restriction are known to be at increased risk for long term neurodevelopmental delay into adulthood. The main mechanism for this is likely decreased blood flow to the brain secondary to altered placental blood flow. Antioxidants may serve to protect the developing br...
What is the current status of trial NCT00788866?
This trial is currently completed. It is a NA study. The enrollment target is 80 participants. The study started on 2008-12. Estimated completion is 2014-10.
What interventions are being tested in trial NCT00788866?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Pomegranate Juice (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00788866?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00788866's enrollment target sits among peer trials
80 994th of 2000 higher than 941 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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