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NCT00785798 · ClinicalTrials.gov registry record · Phase 1

Vorinostat and Pegylated Liposomal Doxorubicin in Relapsed or Refractory Lymphomas

A Phase 1 study, sponsored by Yale University.

Terminated
Registry status
Phase 1
Development phase
17
Enrollment target

NCT00785798: Clinical Trial Phase 1 study, sponsored by Yale University.

NCT00785798 is a Phase 1 study that was terminated before completion, run by Yale University. The registered enrollment target is 17 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00785798, a Phase 1 study, was terminated before completion, sponsored by Yale University.

TERMINATED
Registry status
Phase 1
Development phase
17 participants
Enrollment target

Study Summary

The study will be a dose-finding, phase I study of the combination of vorinostat and PLD in patients with advanced lymphoma refractory to at least one prior systemic therapy.

Primary Outcome

number of patients responding

Interventions

  • DRUG Vorinostat
  • DRUG Pegylated Liposomal Doxorubicin (PLD), Doxil

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2009-01
Est. Completion 2011-09
Phase Phase 1
Yale University

1,492 total trials

Why NCT00785798 stopped before completion

NCT00785798 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% lower).

The record links to 0 conditions, and to 2 interventions - of which Vorinostat is the first listed.

NCT00785798 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00785798 about?

NCT00785798 is a clinical study titled "Vorinostat and Pegylated Liposomal Doxorubicin in Relapsed or Refractory Lymphomas". The study will be a dose-finding, phase I study of the combination of vorinostat and PLD in patients with advanced lymphoma refractory to at least one prior systemic therapy.

What is the current status of trial NCT00785798?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2009-01. Estimated completion is 2011-09.

What interventions are being tested in trial NCT00785798?

The interventions under investigation include: Vorinostat (DRUG), Pegylated Liposomal Doxorubicin (PLD), Doxil (DRUG).

Who is sponsoring clinical trial NCT00785798?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00785798's enrollment target sits among peer trials

17 1785th of 2000 higher than 215 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00785798, the US trial registry maintained by the National Library of Medicine. NCT00785798 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.