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NCT00769470 · ClinicalTrials.gov registry record · Phase 2
Docetaxel, Carboplatin, and Trastuzumab and/or Lapatinib in Treating Women With Stage I, Stage II, or Stage III Breast Cancer That Can Be Removed by Surgery
A Phase 2 study of Breast Cancer, sponsored by Translational Oncology Research International.
- Completed
- Registry status
- Phase 2
- Development phase
- 18
- Enrollment target
- 15
- Study locations
NCT00769470: Completed Phase 2 study of Breast Cancer, sponsored by Translational Oncology Research International.
NCT00769470 is a Phase 2 study of Breast Cancer that has completed, run by Translational Oncology Research International. The registered enrollment target is 18 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 15 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00769470, a Phase 2 study of Breast Cancer, has completed, sponsored by Translational Oncology Research International.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 18 participants
- Enrollment target
- 15
- Study locations
Study Summary
RATIONALE: Drugs used in chemotherapy, such as docetaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as trastuzumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Lapatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether docetaxel and carboplatin are more effective when given together with trastuzumab and/or lapatinib in treating women with stage I, stage II, or stage III breast cancer. PURPOSE: This randomized phase II trial is studying how well docetaxel and carboplatin work when given together with trastuzumab and/or lapatinib in treating women with stage I, stage II, or stage III breast cancer that can be removed by surgery.
Conditions Studied
Interventions
- DRUG carboplatin
- DRUG docetaxel
- BIOLOGICAL trastuzumab
- DRUG lapatinib ditosylate
Study Locations (15)
California
- Central Hematology Oncology Medical Group, Incorporated - Alhambra - Alhambra
- Comprehensive Blood and Cancer Center - Bakersfield
- St. Jude Heritage Medical Group at Virginia K. Crosson Cancer Center - Fullerton
- North Valley Hematology-Oncology Medical Group - Northridge
- Wilshire Oncology Medical Group, Incorporated - Pomona - Pomona
- Sansum Medical Clinic - Santa Barbara
- Central Coast Medical Oncology Corporation - Santa Maria
- Santa Barbara Hematology Oncology - Solvang - Solvang
- Cancer Care Associates Medical Group, Incorporated - Redondo Beach - Torrance
Florida
- Cancer Institute of Florida, PA - Orlando - Orlando
- Florida Hospital Cancer Institute - Orlando
- Hematology and Oncology Consultants, PA - Orlando - Orlando
Indiana
- Providence Medical Group - Haute Terre
Nevada
- Comprehensive Cancer Centers of Nevada - Henderson - Henderson
New Mexico
- New Mexico Cancer Center - Albuquerque
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2009-04 |
| Phase | Phase 2 |
What the finished NCT00769470 record still lists
NCT00769470 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 4 interventions - of which carboplatin is the first listed.
NCT00769470 lists 15 locations in 5 states (California, Florida, Indiana).
Frequently Asked Questions
What is clinical trial NCT00769470 about?
NCT00769470 is a clinical study titled "Docetaxel, Carboplatin, and Trastuzumab and/or Lapatinib in Treating Women With Stage I, Stage II, or Stage III Breast Cancer That Can Be Removed by Surgery". RATIONALE: Drugs used in chemotherapy, such as docetaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as trastuzumab, can block tumor growth in different ways. Some block the abil...
What is the current status of trial NCT00769470?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2009-04.
What conditions does trial NCT00769470 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT00769470?
The interventions under investigation include: carboplatin (DRUG), docetaxel (DRUG), trastuzumab (BIOLOGICAL), lapatinib ditosylate (DRUG).
Who is sponsoring clinical trial NCT00769470?
This trial is sponsored by Translational Oncology Research International, which has 11 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00769470 being conducted?
This trial has 15 study locations across California, Florida, Indiana, Nevada, New Mexico. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00769470's enrollment target sits among peer trials
18 1118th of 1224 higher than 97 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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