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NCT00759291 · ClinicalTrials.gov registry record · Phase 2
The Impact of Free Fatty Acid Reduction on Vascular Function in the Metabolic Syndrome
A Phase 2 study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
NCT00759291: Completed Phase 2 study, sponsored by Brigham and Women's Hospital.
NCT00759291 is a Phase 2 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00759291, a Phase 2 study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
Study Summary
This study will test the hypothesis that reducing the release of free fatty acids (FFA) from fat cells will restore insulin-mediated, endothelium-dependent vasodilation in people with the metabolic syndrome.
Primary Outcome
Brachial artery response to a 5 minute blood pressure cuff-applied ischemic period
Interventions
- DRUG Placebo
- DRUG acipimox
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2006-04-01 |
| Est. Completion | 2017-12-30 |
| Phase | Phase 2 |
What the finished NCT00759291 record still lists
NCT00759291 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00759291 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00759291 about?
NCT00759291 is a clinical study titled "The Impact of Free Fatty Acid Reduction on Vascular Function in the Metabolic Syndrome". This study will test the hypothesis that reducing the release of free fatty acids (FFA) from fat cells will restore insulin-mediated, endothelium-dependent vasodilation in people with the metabolic syndrome.
What is the current status of trial NCT00759291?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2006-04-01. Estimated completion is 2017-12-30.
What interventions are being tested in trial NCT00759291?
The interventions under investigation include: Placebo (DRUG), acipimox (DRUG).
Who is sponsoring clinical trial NCT00759291?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00759291's enrollment target sits among peer trials
40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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