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NCT00757588 · ClinicalTrials.gov registry record · Phase 3
Safety and Efficacy of Saxagliptin Plus Insulin With or Without Metformin
A Phase 3 study of Type 2 Diabetes, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 3
- Development phase
- 455
- Enrollment target
- 20
- Study locations
NCT00757588 is a Phase 3 study of Type 2 Diabetes that has completed, run by AstraZeneca. The registered enrollment target is 455 participants, below the 1,101-participant average among 288 other Type 2 Diabetes trials with a reported enrollment target (59% lower). The trial reports 20 study locations across 13 states.
The verdict
NCT00757588, a Phase 3 study of Type 2 Diabetes, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 455 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to compare the effects of saxagliptin with those of placebo as add-on therapy to insulin and insulin with metformin in improving glycemic control at 24 and 52 weeks.
Conditions Studied
Interventions
- DRUG Saxagliptin, 5 mg + insulin
- DRUG Placebo + insulin
Study Locations (20)
California
- Valley Research - Fresno
- Torrance-Lomita Medical Center - Lomita
- Diabetes Medical Center Of California - Northridge
- Ritchken & First M.D.'S - San Diego
- Encompass Clinical Research - Spring Valley
Florida
- Central Florida Clinical Trials, Inc. - Altamonte Springs
- Family Care Associates Of Nw Florida - Chipley
- Panhandle Family Care Assoc. & Coastal Palms Res. Grp Inc. - Marianna
Texas
- Texas Center For Drug Development - Houston
- Dgd Research, Inc. - San Antonio
Arizona
- Clinical Research Advantage, Inc - Tempe
Georgia
- Endocrine Research Solutions, Inc. - Roswell
Mississippi
- Danny W. Jackson P.A. - Rolling Fork
New York
- Southgate Medical Group - West Seneca
South Carolina
- Southeastern Research Associates, Inc. - Taylors
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 455 participants |
| Start Date | 2008-11 |
| Est. Completion | 2010-04 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00757588
The ClinicalTrials.gov registry entry for NCT00757588 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 455 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,101-participant average among 288 other Type 2 Diabetes trials with a reported enrollment target (59% lower). The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Type 2 Diabetes appearing as the primary indexed condition, and to 2 interventions - of which Saxagliptin, 5 mg + insulin is the first listed.
NCT00757588 reports 20 study locations spanning 13 distinct geographic areas - top geographies include California, Florida, Texas.
Frequently Asked Questions
What is clinical trial NCT00757588 about?
NCT00757588 is a clinical study titled "Safety and Efficacy of Saxagliptin Plus Insulin With or Without Metformin". The purpose of this study is to compare the effects of saxagliptin with those of placebo as add-on therapy to insulin and insulin with metformin in improving glycemic control at 24 and 52 weeks.
What is the current status of trial NCT00757588?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 455 participants. The study started on 2008-11. Estimated completion is 2010-04.
What conditions does trial NCT00757588 study?
This clinical trial studies the following conditions: Type 2 Diabetes.
What interventions are being tested in trial NCT00757588?
The interventions under investigation include: Saxagliptin, 5 mg + insulin (DRUG), Placebo + insulin (DRUG).
Who is sponsoring clinical trial NCT00757588?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00757588 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Georgia, Mississippi. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.