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NCT00756717 · ClinicalTrials.gov registry record · Phase 4

Study Of MK-0752 In Combination With Tamoxifen Or Letrozole to Treat Early Stage Breast Cancer

A Phase 4 study of Breast Cancer, sponsored by Loyola University.

Completed
Registry status
Phase 4
Development phase
22
Enrollment target
1
Study location

NCT00756717: Completed Phase 4 study of Breast Cancer, sponsored by Loyola University.

NCT00756717 is a Phase 4 study of Breast Cancer that has completed, run by Loyola University. The registered enrollment target is 22 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00756717, a Phase 4 study of Breast Cancer, has completed, sponsored by Loyola University.

COMPLETED
Registry status
Phase 4
Development phase
22 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research project is to study the effect of a research (investigational) drug, MK-0752 combined with either tamoxifen or letrozole on breast cancer cells. Tamoxifen and letrozole are standard hormone treatments used to treat breast cancers that are positive for the estrogen receptor. However, over time the breast cancer cells can become resistant to tamoxifen and letrozole. MK-0752 is in a class of drugs called gamma secretase inhibitors. Gamma secretase inhibitors may play a role in reversing the resistance to drugs such as tamoxifen and letrozole.

Conditions Studied

Breast Cancer

Interventions

  • DRUG MK-0752

Study Locations (1)

Illinois

  • Loyola Univeristy Medical Center, Cardinal Bernardin Cancer Center - Maywood

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2008-02-14
Est. Completion 2011-12-21
Phase Phase 4

Sponsor

Loyola University

92 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00756717

The ClinicalTrials.gov registry entry for NCT00756717 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The listed sponsor is Loyola University, which has 92 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which MK-0752 is the first listed.

NCT00756717 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT00756717 about?

NCT00756717 is a clinical study titled "Study Of MK-0752 In Combination With Tamoxifen Or Letrozole to Treat Early Stage Breast Cancer". The purpose of this research project is to study the effect of a research (investigational) drug, MK-0752 combined with either tamoxifen or letrozole on breast cancer cells. Tamoxifen and letrozole are standard hormone treatments used to treat breast cancers that are positive for the estrogen recep...

What is the current status of trial NCT00756717?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 22 participants. The study started on 2008-02-14. Estimated completion is 2011-12-21.

What conditions does trial NCT00756717 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT00756717?

The interventions under investigation include: MK-0752 (DRUG).

Who is sponsoring clinical trial NCT00756717?

This trial is sponsored by Loyola University, which has 92 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00756717 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.