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NCT00750737 · ClinicalTrials.gov registry record · Phase 3
Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC)
A Phase 3 study of Hematologic Malignancies and Invasive Fungal Infections, sponsored by M.D. Anderson Cancer Center.
- Completed
- Registry status
- Phase 3
- Development phase
- 46
- Enrollment target
- 1
- Study location
NCT00750737: Completed Phase 3 study of Hematologic Malignancies and Invasive Fungal Infections, sponsored by M.D. Anderson Cancer Center.
NCT00750737 is a Phase 3 study of Hematologic Malignancies and Invasive Fungal Infections that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 46 participants, below the 2,711-participant average among 45 other Hematologic Malignancies trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00750737, a Phase 3 study of Hematologic Malignancies and Invasive Fungal Infections, has completed, sponsored by M.D. Anderson Cancer Center.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 46 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this study is to compare the safety and efficacy of ABLC versus oral Posaconazole in the prevention of invasive fungal infections in high risk patients with hematologic malignancies or hematopoietic stem cell transplant. Primary objective is to demonstrate the low toxicity rate and low rate of invasive fungal infections associated with ABLC or Posaconazole prophylaxis. Secondary objective will be to compare the cost effectiveness of these two prophylactic regimens.
Primary Outcome
Percentage of participants that developed IFI within 7 days of antifungal prophylaxis therapy (Posaconazole or ABLC).
Conditions Studied
Interventions
- DRUG Posaconazole
- DRUG ABLC
Study Locations (1)
Texas
- UT MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2008-06 |
| Est. Completion | 2012-06 |
| Phase | Phase 3 |
What the finished NCT00750737 record still lists
NCT00750737 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 2,711-participant average among 45 other Hematologic Malignancies trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Hematologic Malignancies appearing as the primary indexed condition, and to 2 interventions - of which Posaconazole is the first listed.
NCT00750737 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT00750737 about?
NCT00750737 is a clinical study titled "Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC)". The objective of this study is to compare the safety and efficacy of ABLC versus oral Posaconazole in the prevention of invasive fungal infections in high risk patients with hematologic malignancies or hematopoietic stem cell transplant. Primary objective is to demonstrate the low toxicity rate and...
What is the current status of trial NCT00750737?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 46 participants. The study started on 2008-06. Estimated completion is 2012-06.
What conditions does trial NCT00750737 study?
This clinical trial studies the following conditions: Hematologic Malignancies, Invasive Fungal Infections.
What interventions are being tested in trial NCT00750737?
The interventions under investigation include: Posaconazole (DRUG), ABLC (DRUG).
Who is sponsoring clinical trial NCT00750737?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00750737 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00750737's enrollment target sits among peer trials
46 27th of 45 higher than 19 of 45 other Hematologic Malignancies trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hematologic Malignancies trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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