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NCT00729911 · ClinicalTrials.gov registry record · Phase 4

Ablation vs Amiodarone for Treatment of AFib in Patients With CHF and an ICD

A Phase 4 study of Heart Failure, sponsored by Texas Cardiac Arrhythmia Research Foundation.

Completed
Registry status
Phase 4
Development phase
203
Enrollment target
1
Study location

NCT00729911: Completed Phase 4 study of Heart Failure, sponsored by Texas Cardiac Arrhythmia Research Foundation.

NCT00729911 is a Phase 4 study of Heart Failure that has completed, run by Texas Cardiac Arrhythmia Research Foundation. The registered enrollment target is 203 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00729911, a Phase 4 study of Heart Failure, has completed, sponsored by Texas Cardiac Arrhythmia Research Foundation.

COMPLETED
Registry status
Phase 4
Development phase
203 participants
Enrollment target
1
Study location

Study Summary

1. To determine if catheter-based atrial fibrillation (AF) ablation is superior to Amiodarone treatment for symptomatic persistent/permanent AF in ICD/CRTD patients with an impaired left ventricular function. 2. Hypothesis: AF ablation is better than Amiodarone for subjects with symptomatic persistent or permanent AF and impaired LV function in terms of recurrence of AF, quality of life, 6-minute walk distance, EF and total number of hospitalizations.

Conditions Studied

Interventions

  • DRUG Amiodarone
  • PROCEDURE Atrial Fibrillation ablation

Study Locations (1)

Texas

  • Texas Cardiac Arrhythmia Research Foundation - Austin

Trial Details

FieldValue
Enrollment Target 203 participants
Start Date 2008-10
Est. Completion 2015-12
Phase Phase 4

What the finished NCT00729911 record still lists

NCT00729911 is an interventional study that assigns participants to a tested intervention. The registered 203 participants enrollment target is mid-sized for trials with a published cap, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (90% lower).

The record links to 1 condition, with Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Amiodarone is the first listed.

NCT00729911 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT00729911 about?

NCT00729911 is a clinical study titled "Ablation vs Amiodarone for Treatment of AFib in Patients With CHF and an ICD". 1. To determine if catheter-based atrial fibrillation (AF) ablation is superior to Amiodarone treatment for symptomatic persistent/permanent AF in ICD/CRTD patients with an impaired left ventricular function. 2. Hypothesis: AF ablation is better than Amiodarone for subjects with symptomatic persiste...

What is the current status of trial NCT00729911?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 203 participants. The study started on 2008-10. Estimated completion is 2015-12.

What conditions does trial NCT00729911 study?

This clinical trial studies the following conditions: Heart Failure.

What interventions are being tested in trial NCT00729911?

The interventions under investigation include: Amiodarone (DRUG), Atrial Fibrillation ablation (PROCEDURE).

Who is sponsoring clinical trial NCT00729911?

This trial is sponsored by Texas Cardiac Arrhythmia Research Foundation, which has 15 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00729911 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Heart Failure

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00729911's enrollment target sits among peer trials

203 163rd of 397 higher than 235 of 397 other Heart Failure trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00729911, the US trial registry maintained by the National Library of Medicine. NCT00729911 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.