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NCT00729261 · ClinicalTrials.gov registry record · Phase 1

A Prospective Trial of Elective Extubation in Brain Injured Patients.

A Phase 1 study of Brain Injury, sponsored by Mayo Clinic.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target
1
Study location

NCT00729261 is a Phase 1 study of Brain Injury that has completed, run by Mayo Clinic. The registered enrollment target is 16 participants, below the 5,189-participant average among 10 other Brain Injury trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00729261, a Phase 1 study of Brain Injury, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target
1
Study location

Study Summary

Identifying the optimal time of extubation in a brain injured population should improve patient outcome. Brain injured patients usually remain intubated due to concerns of airway maintenance. Current practice argues that unconscious patients need to remain intubated to protect their airways. More recent data however suggests that delaying extubation in this population increases pneumonias and worsens patient outcomes. We designed a safety and feasibility study of randomizing brain injured patients into early or delayed extubation. The purpose was to gain insight into patient safety concerns and to obtain estimates of sample size needed for a larger study.

Conditions Studied

Interventions

  • PROCEDURE extubation
  • PROCEDURE continued intubation

Study Locations (1)

Minnesota

  • Mayo Clinic - Rochester

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2004-08
Est. Completion 2006-05
Phase Phase 1

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT00729261

The ClinicalTrials.gov registry entry for NCT00729261 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,189-participant average among 10 other Brain Injury trials with a reported enrollment target (100% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Brain Injury appearing as the primary indexed condition, and to 2 interventions - of which extubation is the first listed.

NCT00729261 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT00729261 about?

NCT00729261 is a clinical study titled "A Prospective Trial of Elective Extubation in Brain Injured Patients.". Identifying the optimal time of extubation in a brain injured population should improve patient outcome. Brain injured patients usually remain intubated due to concerns of airway maintenance. Current practice argues that unconscious patients need to remain intubated to protect their airways. More re...

What is the current status of trial NCT00729261?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2004-08. Estimated completion is 2006-05.

What conditions does trial NCT00729261 study?

This clinical trial studies the following conditions: Brain Injury.

What interventions are being tested in trial NCT00729261?

The interventions under investigation include: extubation (PROCEDURE), continued intubation (PROCEDURE).

Who is sponsoring clinical trial NCT00729261?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00729261 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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