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NCT00729118 · ClinicalTrials.gov registry record · Phase 1

Vorinostat and Lenalidomide After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma

A Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm, sponsored by Ohio State University Comprehensive Cancer Center.

Completed
Registry status
Phase 1
Development phase
19
Enrollment target
1
Study location

NCT00729118 is a Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm that has completed, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 19 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00729118, a Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm, has completed, sponsored by Ohio State University Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
19 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Vorinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Lenalidomide may stop the growth of multiple myeloma by blocking blood flow to the cancer. Giving vorinostat together with lenalidomide may kill more cancer cells. PURPOSE: This phase I trial is studying the side effects and best dose of vorinostat when given together with lenalidomide after autologous stem cell transplant in treating patients with multiple myeloma.

Interventions

  • DRUG vorinostat
  • DRUG lenalidomide

Study Locations (1)

Ohio

  • Ohio State University - Columbus

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2008-09-26
Est. Completion 2020-05-04
Phase Phase 1

What the Registry Record Tells You About NCT00729118

The ClinicalTrials.gov registry entry for NCT00729118 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (97% lower). The listed sponsor is Ohio State University Comprehensive Cancer Center, which has 341 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 2 interventions - of which vorinostat is the first listed.

NCT00729118 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT00729118 about?

NCT00729118 is a clinical study titled "Vorinostat and Lenalidomide After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma". RATIONALE: Vorinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Lenalidomide may stop the growth of multiple myeloma by blocking blood flow to the cancer. Giving vorinostat together with lenalidomide may kill more cancer cells. PURPOSE: This phase I...

What is the current status of trial NCT00729118?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2008-09-26. Estimated completion is 2020-05-04.

What conditions does trial NCT00729118 study?

This clinical trial studies the following conditions: Multiple Myeloma, Plasma Cell Neoplasm.

What interventions are being tested in trial NCT00729118?

The interventions under investigation include: vorinostat (DRUG), lenalidomide (DRUG).

Who is sponsoring clinical trial NCT00729118?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00729118 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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