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NCT00729118 · ClinicalTrials.gov registry record · Phase 1
Vorinostat and Lenalidomide After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma
A Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm, sponsored by Ohio State University Comprehensive Cancer Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT00729118: Completed Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm, sponsored by Ohio State University Comprehensive Cancer Center.
NCT00729118 is a Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm that has completed, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 19 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00729118, a Phase 1 study of Multiple Myeloma and Plasma Cell Neoplasm, has completed, sponsored by Ohio State University Comprehensive Cancer Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
RATIONALE: Vorinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Lenalidomide may stop the growth of multiple myeloma by blocking blood flow to the cancer. Giving vorinostat together with lenalidomide may kill more cancer cells. PURPOSE: This phase I trial is studying the side effects and best dose of vorinostat when given together with lenalidomide after autologous stem cell transplant in treating patients with multiple myeloma.
Primary Outcome
Patients will be assessed for Adverse events using the NCI CTCAE version 4.0 criteria
Conditions Studied
Interventions
- DRUG vorinostat
- DRUG lenalidomide
Study Locations (1)
Ohio
- Ohio State University - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2008-09-26 |
| Est. Completion | 2020-05-04 |
| Phase | Phase 1 |
What the finished NCT00729118 record still lists
NCT00729118 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 2 interventions - of which vorinostat is the first listed.
NCT00729118 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT00729118 about?
NCT00729118 is a clinical study titled "Vorinostat and Lenalidomide After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma". RATIONALE: Vorinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Lenalidomide may stop the growth of multiple myeloma by blocking blood flow to the cancer. Giving vorinostat together with lenalidomide may kill more cancer cells. PURPOSE: This phase I...
What is the current status of trial NCT00729118?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2008-09-26. Estimated completion is 2020-05-04.
What conditions does trial NCT00729118 study?
This clinical trial studies the following conditions: Multiple Myeloma, Plasma Cell Neoplasm.
What interventions are being tested in trial NCT00729118?
The interventions under investigation include: vorinostat (DRUG), lenalidomide (DRUG).
Who is sponsoring clinical trial NCT00729118?
This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00729118 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Myeloma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00729118's enrollment target sits among peer trials
19 393rd of 438 higher than 46 of 438 other Multiple Myeloma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Myeloma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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