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NCT00714220 · ClinicalTrials.gov registry record
Quantitative Measurement of Nutritional Substrate Utilization in Patients With Amyotrophic Lateral Sclerosis (ALS)
A clinical trial, sponsored by Drexel University College of Medicine.
- Terminated
- Registry status
- 107
- Enrollment target
NCT00714220: Clinical Trial study, sponsored by Drexel University College of Medicine.
NCT00714220 is a clinical trial that was terminated before completion, run by Drexel University College of Medicine. The registered enrollment target is 107 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00714220 was terminated before completion, sponsored by Drexel University College of Medicine.
- TERMINATED
- Registry status
- 107 participants
- Enrollment target
Study Summary
The work of Nau et. al (Nau KL, Bromberg MB, Forshew DA, Katcha Vl. Individuals with amyotrophic lateral sclerosis are in caloric balance despite losses in mass. J Neurol Sci 1995;129 :47-49) showed that patients in the early stages of ALS initially increase their body fat. Another study showed that advanced ALS patients on mechanical ventilation were actually hypometabolic, supporting a hypothesis that ALS patients' daily oral intakes of calories fail to match their energy requirements, thus exacerbating their condition. This current study investigates and compares substrate utilization using a metabolic cart in controls and in ALS patients who are on and off ventilatory support to examine differences in substrate utilization between the two groups of ALS patients and the controls. (Substrate utilization is essentially the percentage of fats, carbohydrates, and protein utilized by the body.) The study will increase our understanding of the nutritional needs of ALS patients and improve our ability to provide the best possible nutrition in progressive illness.
Primary Outcome
Indirect calorimetry will be used to determine how many calories you are burning and how much of your total calories burned are fats.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 107 participants |
| Start Date | 2006-11 |
| Est. Completion | 2014-09 |
Why NCT00714220 stopped before completion
NCT00714220 is an observational study that tracks outcomes without assigning an intervention. The registered 107 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00714220 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00714220 about?
NCT00714220 is a clinical study titled "Quantitative Measurement of Nutritional Substrate Utilization in Patients With Amyotrophic Lateral Sclerosis (ALS)". The work of Nau et. al (Nau KL, Bromberg MB, Forshew DA, Katcha Vl. Individuals with amyotrophic lateral sclerosis are in caloric balance despite losses in mass. J Neurol Sci 1995;129 :47-49) showed that patients in the early stages of ALS initially increase their body fat. Another study showed that...
What is the current status of trial NCT00714220?
This trial is currently terminated. The enrollment target is 107 participants. The study started on 2006-11. Estimated completion is 2014-09.
Who is sponsoring clinical trial NCT00714220?
This trial is sponsored by Drexel University College of Medicine, which has 25 total clinical trials registered on ClinicalTrials.gov.
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