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NCT00711464 · ClinicalTrials.gov registry record · Phase 4
Modafinil Effects on Cognition in Schizophrenia Patients
A Phase 4 study, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- Phase 4
- Development phase
- 29
- Enrollment target
NCT00711464: Completed Phase 4 study, sponsored by University of California, Los Angeles.
NCT00711464 is a Phase 4 study that has completed, run by University of California, Los Angeles. The registered enrollment target is 29 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00711464, a Phase 4 study, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 29 participants
- Enrollment target
Study Summary
Patients with schizophrenia have problems in thinking, known as cognitive dysfunction. This includes many types of cognitive dysfunction, such as in attention, memory and language. These problems may explain why patients with schizophrenia think and act in unusual ways, and often have problems managing aspects of their lives that healthy adults take for granted. Unfortunately, the biochemical aspects of these dysfunctions are presently unknown, and it is not clear whether current psychiatric medications can improve these functions. A recent FDA-approved medication that may improve this function is modafinil. Studies in animals and healthy adults show that this medication can improve many of these cognitive functions. We plan to study the effects of modafinil on these cognitive processes, by giving various doses of this medication to patients before they perform tasks of these cognitive processes. We predict that when patients receive modafinil, they will perform better on a cognitive test, and that these benefits will depend on the dose given.
Primary Outcome
Percent Accuracy on high-control (i.e. difficult) condition on test of cognitive control
Interventions
- DRUG modafinil (M1, M2, M4)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2008-05 |
| Est. Completion | 2012-07 |
| Phase | Phase 4 |
What the finished NCT00711464 record still lists
NCT00711464 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 1 intervention - of which modafinil (M1, M2, M4) is the first listed.
NCT00711464 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00711464 about?
NCT00711464 is a clinical study titled "Modafinil Effects on Cognition in Schizophrenia Patients". Patients with schizophrenia have problems in thinking, known as cognitive dysfunction. This includes many types of cognitive dysfunction, such as in attention, memory and language. These problems may explain why patients with schizophrenia think and act in unusual ways, and often have problems manag...
What is the current status of trial NCT00711464?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 29 participants. The study started on 2008-05. Estimated completion is 2012-07.
What interventions are being tested in trial NCT00711464?
The interventions under investigation include: modafinil (M1, M2, M4) (DRUG).
Who is sponsoring clinical trial NCT00711464?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00711464's enrollment target sits among peer trials
29 1634th of 2000 higher than 366 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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