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NCT00709527 · ClinicalTrials.gov registry record · Phase 1
ARC1905 (Anti-C5 Aptamer) Given With Lucentis 0.5 mg In People With Neovascular Age-Related Macular Degeneration
A Phase 1 study of Neovascular Age-related Macular Degeneration, sponsored by Ophthotech Corporation.
- Completed
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT00709527: Completed Phase 1 study of Neovascular Age-related Macular Degeneration, sponsored by Ophthotech Corporation.
NCT00709527 is a Phase 1 study of Neovascular Age-related Macular Degeneration that has completed, run by Ophthotech Corporation. The registered enrollment target is 60 participants, below the 407-participant average among 33 other Neovascular Age-related Macular Degeneration trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00709527, a Phase 1 study of Neovascular Age-related Macular Degeneration, has completed, sponsored by Ophthotech Corporation.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The objectives of this study are to evaluate the safety, tolerability, and pharmacokinetic profile of multiple doses of ARC1905 intravitreous injection when administered in combination with multiple doses of Lucentis® 0.5 mg/eye, or with one induction dose of Lucentis 0.5 mg/eye in subjects with subfoveal choroidal neovascularization secondary to age-related macular degeneration (AMD).
Conditions Studied
Interventions
- DRUG Avacincaptad Pegol
Study Locations (1)
New York
- Ophthotech Corp - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2008-10-16 |
| Est. Completion | 2009-12-30 |
| Phase | Phase 1 |
What the finished NCT00709527 record still lists
NCT00709527 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 407-participant average among 33 other Neovascular Age-related Macular Degeneration trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Neovascular Age-related Macular Degeneration appearing as the primary indexed condition, and to 1 intervention - of which Avacincaptad Pegol is the first listed.
NCT00709527 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT00709527 about?
NCT00709527 is a clinical study titled "ARC1905 (Anti-C5 Aptamer) Given With Lucentis 0.5 mg In People With Neovascular Age-Related Macular Degeneration". The objectives of this study are to evaluate the safety, tolerability, and pharmacokinetic profile of multiple doses of ARC1905 intravitreous injection when administered in combination with multiple doses of Lucentis® 0.5 mg/eye, or with one induction dose of Lucentis 0.5 mg/eye in subjects with sub...
What is the current status of trial NCT00709527?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2008-10-16. Estimated completion is 2009-12-30.
What conditions does trial NCT00709527 study?
This clinical trial studies the following conditions: Neovascular Age-related Macular Degeneration.
What interventions are being tested in trial NCT00709527?
The interventions under investigation include: Avacincaptad Pegol (DRUG).
Who is sponsoring clinical trial NCT00709527?
This trial is sponsored by Ophthotech Corporation, which has 11 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00709527 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Neovascular Age-related Macular Degeneration
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00709527's enrollment target sits among peer trials
60 20th of 33 higher than 13 of 33 other Neovascular Age-related Macular Degeneration trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Neovascular Age-related Macular Degeneration trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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