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NCT00685178 · ClinicalTrials.gov registry record · Phase 2

Clinical Trial of Topiramate for Cocaine Addiction

A Phase 2 study of Cocaine Dependence, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 2
Development phase
250
Enrollment target
1
Study location

NCT00685178 is a Phase 2 study of Cocaine Dependence that has completed, run by Johns Hopkins University. The registered enrollment target is 250 participants, below the 292-participant average among 38 other Cocaine Dependence trials with a reported enrollment target (14% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00685178, a Phase 2 study of Cocaine Dependence, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 2
Development phase
250 participants
Enrollment target
1
Study location

Study Summary

This is an outpatient clinical trial of topiramate for addressing cocaine dependence and reduction of cocaine associated behaviors in opiate dependent drug users maintained on methadone treatment. The study aims to answer whether topiramate 1. is safe and acceptable to methadone patients 2. reduces cocaine use 3. helps with collateral problems such as alcohol abuse, tobacco dependence, anxiety, PTSD and/or pain symptoms. The study will also evaluate topiramate effect on neuro-cognitive performance.

Conditions Studied

Cocaine Dependence

Interventions

  • DRUG topiramate
  • BEHAVIORAL Contingency Reinforcement
  • DRUG placebo + NonCR

Study Locations (1)

Maryland

  • Behavioral Pharmacology Research Unit - Baltimore

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2007-02
Est. Completion 2011-09
Phase Phase 2

Sponsor

Johns Hopkins University

1,448 total trials

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What the Registry Record Tells You About NCT00685178

The ClinicalTrials.gov registry entry for NCT00685178 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 292-participant average among 38 other Cocaine Dependence trials with a reported enrollment target (14% lower). The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cocaine Dependence appearing as the primary indexed condition, and to 3 interventions - of which topiramate is the first listed.

NCT00685178 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00685178 about?

NCT00685178 is a clinical study titled "Clinical Trial of Topiramate for Cocaine Addiction". This is an outpatient clinical trial of topiramate for addressing cocaine dependence and reduction of cocaine associated behaviors in opiate dependent drug users maintained on methadone treatment. The study aims to answer whether topiramate 1. is safe and acceptable to methadone patients 2. reduce...

What is the current status of trial NCT00685178?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 250 participants. The study started on 2007-02. Estimated completion is 2011-09.

What conditions does trial NCT00685178 study?

This clinical trial studies the following conditions: Cocaine Dependence.

What interventions are being tested in trial NCT00685178?

The interventions under investigation include: topiramate (DRUG), Contingency Reinforcement (BEHAVIORAL), placebo + NonCR (DRUG).

Who is sponsoring clinical trial NCT00685178?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00685178 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.