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NCT00685035 · ClinicalTrials.gov registry record · Phase 4
Comparison of Airway Clearance Therapy in Cystic Fibrosis Using the Same VEST Therapy Device But With Different Settings
A Phase 4 study of Cystic Fibrosis, sponsored by University of Minnesota.
- Completed
- Registry status
- Phase 4
- Development phase
- 17
- Enrollment target
- 1
- Study location
NCT00685035: Completed Phase 4 study of Cystic Fibrosis, sponsored by University of Minnesota.
NCT00685035 is a Phase 4 study of Cystic Fibrosis that has completed, run by University of Minnesota. The registered enrollment target is 17 participants, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00685035, a Phase 4 study of Cystic Fibrosis, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 17 participants
- Enrollment target
- 1
- Study location
Study Summary
Our primary hypothesis is that airway clearance therapy with sine waveform HFCWO using higher inflation pressures combined with both low and high oscillator frequencies will result in greater sputum production compared to sine waveform HFCWO with lower inflation pressures and mid-frequency oscillations.
Primary Outcome
All sputum expectorated during all HFCWC sessions was collected in a pre-weighed specimen container and immediately sealed. Half the subjects used higher pressure/mixed frequency on day 1 followed by lower pressure/mid-frequency on day 4. Half the patients performed lower pressure/mid-frequency on day 1 followed by higher pressure/mixed frequency on day 4. All specimens were immediately centrifuged at 21,150 g for 15 min at 4°C, and the supernatant was completely removed to eliminate saliva. The
Conditions Studied
Interventions
- DEVICE HFCWC with higher pressure/variable-frequency settings
- DEVICE HFCWC with lower pressure/mid-frequency settings
Study Locations (1)
Minnesota
- University of Minnesota Medical Center - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2008-05 |
| Est. Completion | 2008-10 |
| Phase | Phase 4 |
What the finished NCT00685035 record still lists
NCT00685035 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Cystic Fibrosis appearing as the primary indexed condition, and to 2 interventions - of which HFCWC with higher pressure/variable-frequency settings is the first listed.
NCT00685035 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT00685035 about?
NCT00685035 is a clinical study titled "Comparison of Airway Clearance Therapy in Cystic Fibrosis Using the Same VEST Therapy Device But With Different Settings". Our primary hypothesis is that airway clearance therapy with sine waveform HFCWO using higher inflation pressures combined with both low and high oscillator frequencies will result in greater sputum production compared to sine waveform HFCWO with lower inflation pressures and mid-frequency oscillati...
What is the current status of trial NCT00685035?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 17 participants. The study started on 2008-05. Estimated completion is 2008-10.
What conditions does trial NCT00685035 study?
This clinical trial studies the following conditions: Cystic Fibrosis.
What interventions are being tested in trial NCT00685035?
The interventions under investigation include: HFCWC with higher pressure/variable-frequency settings (DEVICE), HFCWC with lower pressure/mid-frequency settings (DEVICE).
Who is sponsoring clinical trial NCT00685035?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00685035 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00685035's enrollment target sits among peer trials
17 138th of 169 higher than 31 of 169 other Cystic Fibrosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cystic Fibrosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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