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NCT00683644 · ClinicalTrials.gov registry record · Phase 2
Zinc to Treat Tinnitus in the Elderly
A Phase 2 study of Tinnitus, sponsored by University of Iowa.
- Completed
- Registry status
- Phase 2
- Development phase
- 116
- Enrollment target
- 1
- Study location
NCT00683644: Completed Phase 2 study of Tinnitus, sponsored by University of Iowa.
NCT00683644 is a Phase 2 study of Tinnitus that has completed, run by University of Iowa. The registered enrollment target is 116 participants, below the 12,615-participant average among 24 other Tinnitus trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00683644, a Phase 2 study of Tinnitus, has completed, sponsored by University of Iowa.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 116 participants
- Enrollment target
- 1
- Study location
Study Summary
There is widespread belief and some evidence to indicate that zinc can successfully treat tinnitus. Zinc deficiency is more likely to occur in the elderly . The primary objective of this study is to establish the effectiveness of zinc for the treatment of tinnitus in individuals 60 years of age and older. Subjects will be randomly assigned to either receive zinc daily or a placebo. After 4 months and a 1-month wash-out, the subjects will be crossed over to the other group.
Primary Outcome
Validated questionnaire of tinnitus reactions. Scale 0 (no tinnitus reaction)- 100 (worst tinnitus reaction). Our primary outcome was the difference scores between Tinnitus Handicap Questionnaire (THQ) on baseline and end of treatment on zinc and placebo treatment. As stated by Newman et al., the test-retest variability was 20%, and difference scores greater than this should be considered a significant reduction. Therefore, changes on the difference scores of 20 or greater were considered as a s
Conditions Studied
Interventions
- DRUG Zinc
- DRUG Placebo oral capsule
Study Locations (1)
Iowa
- University of Iowa - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 116 participants |
| Start Date | 2008-01 |
| Est. Completion | 2011-12 |
| Phase | Phase 2 |
What the finished NCT00683644 record still lists
NCT00683644 is an interventional study that assigns participants to a tested intervention. The registered 116 participants enrollment target is mid-sized for trials with a published cap, below the 12,615-participant average among 24 other Tinnitus trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Tinnitus appearing as the primary indexed condition, and to 2 interventions - of which Zinc is the first listed.
NCT00683644 reports a single indexed study location in Iowa.
Frequently Asked Questions
What is clinical trial NCT00683644 about?
NCT00683644 is a clinical study titled "Zinc to Treat Tinnitus in the Elderly". There is widespread belief and some evidence to indicate that zinc can successfully treat tinnitus. Zinc deficiency is more likely to occur in the elderly . The primary objective of this study is to establish the effectiveness of zinc for the treatment of tinnitus in individuals 60 years of age and ...
What is the current status of trial NCT00683644?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 116 participants. The study started on 2008-01. Estimated completion is 2011-12.
What conditions does trial NCT00683644 study?
This clinical trial studies the following conditions: Tinnitus.
What interventions are being tested in trial NCT00683644?
The interventions under investigation include: Zinc (DRUG), Placebo oral capsule (DRUG).
Who is sponsoring clinical trial NCT00683644?
This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00683644 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tinnitus
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00683644's enrollment target sits among peer trials
116 9th of 24 higher than 16 of 24 other Tinnitus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tinnitus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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