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NCT00670982 · ClinicalTrials.gov registry record · Phase 2

Bevacizumab in Combination With Vinorelbine and Trastuzumab for HER2-Positive, Metastatic Breast Cancer

A Phase 2 study, sponsored by Harold J. Burstein, MD, PhD.

Completed
Registry status
Phase 2
Development phase
29
Enrollment target

NCT00670982: Completed Phase 2 study, sponsored by Harold J. Burstein, MD, PhD.

NCT00670982 is a Phase 2 study that has completed, run by Harold J. Burstein, MD, PhD. The registered enrollment target is 29 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00670982, a Phase 2 study, has completed, sponsored by Harold J. Burstein, MD, PhD.

COMPLETED
Registry status
Phase 2
Development phase
29 participants
Enrollment target

Study Summary

The purpose of this research study is to determine the effects of the combination of bevacizumab, vinorelbine, and trastuzumab on participants and their cancer.

Primary Outcome

Percentage of patients on study without progression at one year after first treatment on study.The date of progression was defined as the earliest occurence of any of the following events: progressive disease by RECIST v1.0, date of initiation of new anticancer therapy, or death due to any cause. New anticancer therapy was defined as the addition or initiation of any new agent for treatment of cancer not including trastuzumab, vinorelbine or bevacizumab.

Interventions

  • DRUG bevacizumab
  • DRUG trastuzumab
  • DRUG vinorelbine

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2008-05
Est. Completion 2012-12
Phase Phase 2
Harold J. Burstein, MD, PhD

5 total trials

What the finished NCT00670982 record still lists

NCT00670982 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% lower).

The record links to 0 conditions, and to 3 interventions - of which bevacizumab is the first listed.

NCT00670982 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00670982 about?

NCT00670982 is a clinical study titled "Bevacizumab in Combination With Vinorelbine and Trastuzumab for HER2-Positive, Metastatic Breast Cancer". The purpose of this research study is to determine the effects of the combination of bevacizumab, vinorelbine, and trastuzumab on participants and their cancer.

What is the current status of trial NCT00670982?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2008-05. Estimated completion is 2012-12.

What interventions are being tested in trial NCT00670982?

The interventions under investigation include: bevacizumab (DRUG), trastuzumab (DRUG), vinorelbine (DRUG).

Who is sponsoring clinical trial NCT00670982?

This trial is sponsored by Harold J. Burstein, MD, PhD, which has 5 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00670982's enrollment target sits among peer trials

29 1669th of 2000 higher than 324 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00670982, the US trial registry maintained by the National Library of Medicine. NCT00670982 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.