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NCT00670800 · ClinicalTrials.gov registry record · NA
Study of Brain Function in Women With Insulin Resistant Polycystic Ovary Syndrome
A NA study, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 14
- Enrollment target
NCT00670800: Completed NA study, sponsored by University of Michigan.
NCT00670800 is a NA study that has completed, run by University of Michigan. The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00670800, a NA study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 14 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the effects of insulin resistance on brain function in women with Polycystic Ovary Syndrome (PCOS). PCOS affected women will be evaluated prior to and following 4-month treatment with Metformin. Additionally, brain function in women with PCOS will be compared to the brain activity in normal control subjects with regular menstrual cycles.
Primary Outcome
Mu-opioid binding potential in left nucleus accumbens is measured before and after 4 months of Metformin treatment. Mu-opioid binding potential is measured in vivo with C11-carfentanil positron emission tomography in women with PCOS before and after 4 months of metformin treatment. Binding Potential is measured by the ratio of Mu-opioid receptor concentration (Bmax)/Receptor radiotracer (C11-carfentanil) affinity (Kd.) Control group was measured at baseline only.
Interventions
- DRUG Metformin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2008-01 |
| Est. Completion | 2009-08 |
| Phase | NA |
What the finished NCT00670800 record still lists
NCT00670800 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Metformin is the first listed.
NCT00670800 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00670800 about?
NCT00670800 is a clinical study titled "Study of Brain Function in Women With Insulin Resistant Polycystic Ovary Syndrome". The purpose of this study is to evaluate the effects of insulin resistance on brain function in women with Polycystic Ovary Syndrome (PCOS). PCOS affected women will be evaluated prior to and following 4-month treatment with Metformin. Additionally, brain function in women with PCOS will be compared...
What is the current status of trial NCT00670800?
This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2008-01. Estimated completion is 2009-08.
What interventions are being tested in trial NCT00670800?
The interventions under investigation include: Metformin (DRUG).
Who is sponsoring clinical trial NCT00670800?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00670800's enrollment target sits among peer trials
14 1909th of 2000 higher than 90 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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