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NCT00668395 · ClinicalTrials.gov registry record · NA
Effects of CYP2B6 Genetic Polymorphisms on Efavirenz Pharmacokinetics
A NA study of HIV, sponsored by Indiana University.
- Completed
- Registry status
- NA
- Development phase
- 73
- Enrollment target
- 2
- Study locations
NCT00668395 is a NA study of HIV that has completed, run by Indiana University. The registered enrollment target is 73 participants, below the 440-participant average among 303 other HIV trials with a reported enrollment target (83% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT00668395, a NA study of HIV, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- NA
- Development phase
- 73 participants
- Enrollment target
- 2
- Study locations
Study Summary
1. To see how the liver breaks down efavirenz by an enzyme called CYP2B6. It is suggested that when Efavirenz is taken repeatedly it may increase the amount of CYP2B6 in your liver and thus speed up your liver's ability to get rid of efavirenz from your body. This may render efavirenz and other medications ineffective. 2. To see how efavirenz interact with other drugs taken at the same time with it. 3. To see if genetic differences can change the way how the liver breaks down efavirenz and its interactions with other co-administered drugs.
Conditions Studied
Interventions
- DRUG Efavirenz
Study Locations (2)
Indiana
- Indiana Clinical Research Center (ICRC) - Indianapolis
- Indiana University - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 73 participants |
| Start Date | 2007-05 |
| Est. Completion | 2010-04 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00668395
The ClinicalTrials.gov registry entry for NCT00668395 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 73 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 440-participant average among 303 other HIV trials with a reported enrollment target (83% lower). The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with HIV appearing as the primary indexed condition, and to 1 intervention - of which Efavirenz is the first listed.
NCT00668395 reports 2 study locations spanning 1 distinct geographic area - top geographies include Indiana.
Frequently Asked Questions
What is clinical trial NCT00668395 about?
NCT00668395 is a clinical study titled "Effects of CYP2B6 Genetic Polymorphisms on Efavirenz Pharmacokinetics". 1. To see how the liver breaks down efavirenz by an enzyme called CYP2B6. It is suggested that when Efavirenz is taken repeatedly it may increase the amount of CYP2B6 in your liver and thus speed up your liver's ability to get rid of efavirenz from your body. This may render efavirenz and other medi...
What is the current status of trial NCT00668395?
This trial is currently completed. It is a NA study. The enrollment target is 73 participants. The study started on 2007-05. Estimated completion is 2010-04.
What conditions does trial NCT00668395 study?
This clinical trial studies the following conditions: HIV.
What interventions are being tested in trial NCT00668395?
The interventions under investigation include: Efavirenz (DRUG).
Who is sponsoring clinical trial NCT00668395?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00668395 being conducted?
This trial has 2 study locations across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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