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NCT00668187 · ClinicalTrials.gov registry record

A Natural History Study of the Gangliosidoses

A clinical trial of GM1 Gangliosidosis and Tay-Sachs Disease, sponsored by University of Minnesota.

Recruiting
Registry status
52
Enrollment target
1
Study location

NCT00668187 is a study of GM1 Gangliosidosis and Tay-Sachs Disease that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 52 participants, below the 98-participant average among 6 other GM1 Gangliosidosis trials with a reported enrollment target (47% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00668187, a study of GM1 Gangliosidosis and Tay-Sachs Disease, is actively recruiting participants, sponsored by University of Minnesota.

RECRUITING
Registry status
52 participants
Enrollment target
1
Study location

Study Summary

Hypothesis: To characterize and describe disease progression and heterogeneity of the gangliosidosis diseases. This research study seeks to develop a quantitative method to delineate disease progression for the gangliosidosis diseases (Tay-Sachs disease, Sandhoff disease, and GM1 gangliosidosis) in order to better understand the natural history and heterogeneity of these diseases. Such a quantitative method will also be essential for evaluating any treatments that may become available in the future, such as gene therapy. The data from this study will be necessary to provide end-points for future therapies, guide medical decisions about treatment, provide objective measurement of treatment outcomes, and accurately inform parents regarding potential outcomes.

Study Locations (1)

Minnesota

  • University of Minnesota - Pediatric Genetics and Metabolism - Minneapolis

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2010-12
Est. Completion 2027-03-01

Sponsor

University of Minnesota

966 total trials

What the Registry Record Tells You About NCT00668187

The ClinicalTrials.gov registry entry for NCT00668187 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 98-participant average among 6 other GM1 Gangliosidosis trials with a reported enrollment target (47% lower). The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with GM1 Gangliosidosis appearing as the primary indexed condition, and to 0 interventions.

NCT00668187 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT00668187 about?

NCT00668187 is a clinical study titled "A Natural History Study of the Gangliosidoses". Hypothesis: To characterize and describe disease progression and heterogeneity of the gangliosidosis diseases. This research study seeks to develop a quantitative method to delineate disease progression for the gangliosidosis diseases (Tay-Sachs disease, Sandhoff disease, and GM1 gangliosidosis) in...

What is the current status of trial NCT00668187?

This trial is currently recruiting. The enrollment target is 52 participants. The study started on 2010-12. Estimated completion is 2027-03-01.

What conditions does trial NCT00668187 study?

This clinical trial studies the following conditions: GM1 Gangliosidosis, Tay-Sachs Disease, Sandhoff Disease, GM2 Gangliosidosis, Late Onset Tay-Sachs Disease.

Who is sponsoring clinical trial NCT00668187?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00668187 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.