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NCT00638547 · ClinicalTrials.gov registry record · Phase 1

Intrathecal Enzyme Replacement for Hurler Syndrome

A Phase 1 study of Hurler Syndrome, sponsored by Masonic Cancer Center, University of Minnesota.

Completed
Registry status
Phase 1
Development phase
26
Enrollment target
1
Study location

NCT00638547 is a Phase 1 study of Hurler Syndrome that has completed, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 26 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT00638547, a Phase 1 study of Hurler Syndrome, has completed, sponsored by Masonic Cancer Center, University of Minnesota.

COMPLETED
Registry status
Phase 1
Development phase
26 participants
Enrollment target
1
Study location

Study Summary

This protocol will examine whether the enzyme alpha-L-iduronidase (Laronidase), delivered into the spinal fluid of patients with Hurler syndrome at intervals before and after bone marrow transplant, is a safe and effective approach to slow the neurologic degeneration seen in Hurler patients undergoing transplantation.

Conditions Studied

Interventions

  • DRUG IRT Laronidase

Study Locations (1)

Minnesota

  • University of Minnesota, Fairview - Minneapolis

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2008-01-02
Est. Completion 2018-11-18
Phase Phase 1

What the Registry Record Tells You About NCT00638547

The ClinicalTrials.gov registry entry for NCT00638547 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Masonic Cancer Center, University of Minnesota, which has 249 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hurler Syndrome appearing as the primary indexed condition, and to 1 intervention - of which IRT Laronidase is the first listed.

NCT00638547 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT00638547 about?

NCT00638547 is a clinical study titled "Intrathecal Enzyme Replacement for Hurler Syndrome". This protocol will examine whether the enzyme alpha-L-iduronidase (Laronidase), delivered into the spinal fluid of patients with Hurler syndrome at intervals before and after bone marrow transplant, is a safe and effective approach to slow the neurologic degeneration seen in Hurler patients undergoi...

What is the current status of trial NCT00638547?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2008-01-02. Estimated completion is 2018-11-18.

What conditions does trial NCT00638547 study?

This clinical trial studies the following conditions: Hurler Syndrome.

What interventions are being tested in trial NCT00638547?

The interventions under investigation include: IRT Laronidase (DRUG).

Who is sponsoring clinical trial NCT00638547?

This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00638547 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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