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NCT00630565 · ClinicalTrials.gov registry record · Phase 2

Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia

A Phase 2 study, sponsored by Masonic Cancer Center, University of Minnesota.

Terminated
Registry status
Phase 2
Development phase
12
Enrollment target

NCT00630565: Clinical Trial Phase 2 study, sponsored by Masonic Cancer Center, University of Minnesota.

NCT00630565 is a Phase 2 study that was terminated before completion, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 12 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00630565, a Phase 2 study, was terminated before completion, sponsored by Masonic Cancer Center, University of Minnesota.

TERMINATED
Registry status
Phase 2
Development phase
12 participants
Enrollment target

Study Summary

RATIONALE: Giving chemotherapy and colony-stimulating factors, such as G-CSF, may increase the number of stem cells in the blood. The stem cells are collected from the patient's blood and stored. Chemotherapy or radiation therapy is given to prepare the bone marrow for the stem cell transplant. The stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the chemotherapy and radiation therapy. PURPOSE: This clinical trial is studying how well an autologous stem cell transplant works in treating patients with acute myeloid leukemia.

Primary Outcome

Percentage of Participants with Engraftment measured by myeloid, platelet, and erythroid recovery

Interventions

  • DRUG cyclophosphamide
  • DRUG dexamethasone
  • DRUG etoposide
  • DRUG busulfan
  • BIOLOGICAL sargramostim

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2006-07-26
Est. Completion 2022-07-28
Phase Phase 2

Why NCT00630565 stopped before completion

NCT00630565 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower).

The record links to 0 conditions, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT00630565 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00630565 about?

NCT00630565 is a clinical study titled "Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia". RATIONALE: Giving chemotherapy and colony-stimulating factors, such as G-CSF, may increase the number of stem cells in the blood. The stem cells are collected from the patient's blood and stored. Chemotherapy or radiation therapy is given to prepare the bone marrow for the stem cell transplant. The ...

What is the current status of trial NCT00630565?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2006-07-26. Estimated completion is 2022-07-28.

What interventions are being tested in trial NCT00630565?

The interventions under investigation include: cyclophosphamide (DRUG), dexamethasone (DRUG), etoposide (DRUG), busulfan (DRUG), sargramostim (BIOLOGICAL).

Who is sponsoring clinical trial NCT00630565?

This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00630565's enrollment target sits among peer trials

12 1948th of 2000 higher than 34 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00630565, the US trial registry maintained by the National Library of Medicine. NCT00630565 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.