Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00603603 · ClinicalTrials.gov registry record · NA
Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity
A NA study of Surgical Wound Infection and Infection; Cesarean Section, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 606
- Enrollment target
- 1
- Study location
NCT00603603: Completed NA study of Surgical Wound Infection and Infection; Cesarean Section, sponsored by Washington University School of Medicine.
NCT00603603 is a NA study of Surgical Wound Infection and Infection; Cesarean Section that has completed, run by Washington University School of Medicine. The registered enrollment target is 606 participants, below the 853-participant average among 8 other Surgical Wound Infection trials with a reported enrollment target (29% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00603603, a NA study of Surgical Wound Infection and Infection; Cesarean Section, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 606 participants
- Enrollment target
- 1
- Study location
Study Summary
Previous studies have demonstrated that patients who undergo surgery while they under general anesthesia have fewer wound infections if they receive higher concentrations of oxygen but this has never been studied in women who are undergoing cesarean section. We plan to randomize women who are undergoing cesarean to receive either standard of care oxygen flow through a nasal cannula during their cesarean section only or a higher concentration of oxygen than they would typically receive through a face mask. Women will receive this therapy during their cesarean and for 2 hours afterwards. We will follow them after their surgery for evidence of infection either in their wound or their uterus.
Conditions Studied
Interventions
- OTHER 80% inhaled oxygen via non-rebreather mask
- OTHER 30% inhaled oxygen via nasal cannula
Study Locations (1)
Missouri
- Barnes Jewish Hospital/Washington University School. of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 606 participants |
| Start Date | 2008-02 |
| Est. Completion | 2010-05 |
| Phase | NA |
What the finished NCT00603603 record still lists
NCT00603603 is an interventional study that assigns participants to a tested intervention. The registered 606 participants enrollment target is mid-sized for trials with a published cap, below the 853-participant average among 8 other Surgical Wound Infection trials with a reported enrollment target (29% lower).
The record links to 3 conditions, with Surgical Wound Infection appearing as the primary indexed condition, and to 2 interventions - of which 80% inhaled oxygen via non-rebreather mask is the first listed.
NCT00603603 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT00603603 about?
NCT00603603 is a clinical study titled "Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity". Previous studies have demonstrated that patients who undergo surgery while they under general anesthesia have fewer wound infections if they receive higher concentrations of oxygen but this has never been studied in women who are undergoing cesarean section. We plan to randomize women who are underg...
What is the current status of trial NCT00603603?
This trial is currently completed. It is a NA study. The enrollment target is 606 participants. The study started on 2008-02. Estimated completion is 2010-05.
What conditions does trial NCT00603603 study?
This clinical trial studies the following conditions: Surgical Wound Infection, Infection; Cesarean Section, Endometritis.
What interventions are being tested in trial NCT00603603?
The interventions under investigation include: 80% inhaled oxygen via non-rebreather mask (OTHER), 30% inhaled oxygen via nasal cannula (OTHER).
Who is sponsoring clinical trial NCT00603603?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00603603 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Surgical Wound Infection
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00603603's enrollment target sits among peer trials
606 3rd of 8 higher than 6 of 8 other Surgical Wound Infection trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Surgical Wound Infection trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Reducing Intraoperative ESKAPE Transmission Through Use of a Personal Hand Hygiene System
RECRUITING · NA
-
The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal
RECRUITING · Phase 3
-
Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections
RECRUITING · Phase 3
-
A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections
RECRUITING · Phase 1
-
NPWT in Patients Undergoing Surgical Procedures for Management of GI Malignancies
ACTIVE NOT RECRUITING · Phase 2
-
Local Warming of Surgical Incisions
COMPLETED · Phase 3
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02342444 · 606 participants · Phase 4
Lovenox 30 mg Twice Daily (BID) Versus 40 mg Once Daily (QD)
- NCT02064673 · 608 participants · Phase 3
Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy
- NCT06091202 · 608 participants · Phase 3
Tele-Collaborative Outreach to Rural Patients With Chronic Pain
- NCT06098144 · 608 participants · Phase 4
Smoking Cessation Program in the Construction Sector
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia