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NCT00596609 · ClinicalTrials.gov registry record
Intrathecal Morphine on Transcranial Electric Motor-Evoked Potentials
A clinical trial of Trauma, Nervous System, sponsored by Children's Hospital of Philadelphia.
- Completed
- Registry status
- 36
- Enrollment target
- 1
- Study location
NCT00596609: Completed study of Trauma, Nervous System, sponsored by Children's Hospital of Philadelphia.
NCT00596609 is a study of Trauma, Nervous System that has completed, run by Children's Hospital of Philadelphia. The registered enrollment target is 36 participants, below the 74-participant average among 5 other Trauma, Nervous System trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00596609, a study of Trauma, Nervous System, has completed, sponsored by Children's Hospital of Philadelphia.
- COMPLETED
- Registry status
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients undergoing posterior spinal fusion (PSF) procedures for scoliosis are at risk for iatrogenic neurologic injury of the spinal cord and/or spinal nerve roots during surgical correction of the abnormal spinal curvature. The degree of neurologic injury can range from minor sensory deficits to complete paraplegia. Surgeons at CHOP utilize neurophysiologists to identify impending neurologic injury. These consultants monitor spinal cord pathways by recording and analyzing evoked potentials during the operation. Evoked potentials are low voltage electrical signals generated in response to transcranial or transcutaneous electrical stimulation of motor and sensory neural pathways. Some patients undergoing PSF receive an injection of morphine into the cerebrospinal fluid during the operation. This intrathecal (IT) morphine has potent analgesic effects. While most commonly used anesthetic agents have well-characterized effects on evoked potentials, little data exists on the effects of IT morphine on transcranial electric motor-evoked potentials (TceMEPs). This is a prospective observational study to characterize the effects of IT morphine on TceMEPs.
Conditions Studied
Interventions
- DRUG Intrathecal Morphine
Study Locations (1)
Pennsylvania
- The Children's Hospital of Philadephia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2007-08 |
| Est. Completion | 2009-04 |
What the finished NCT00596609 record still lists
NCT00596609 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 74-participant average among 5 other Trauma, Nervous System trials with a reported enrollment target (51% lower).
The record links to 1 condition, with Trauma, Nervous System appearing as the primary indexed condition, and to 1 intervention - of which Intrathecal Morphine is the first listed.
NCT00596609 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00596609 about?
NCT00596609 is a clinical study titled "Intrathecal Morphine on Transcranial Electric Motor-Evoked Potentials". Patients undergoing posterior spinal fusion (PSF) procedures for scoliosis are at risk for iatrogenic neurologic injury of the spinal cord and/or spinal nerve roots during surgical correction of the abnormal spinal curvature. The degree of neurologic injury can range from minor sensory deficits to c...
What is the current status of trial NCT00596609?
This trial is currently completed. The enrollment target is 36 participants. The study started on 2007-08. Estimated completion is 2009-04.
What conditions does trial NCT00596609 study?
This clinical trial studies the following conditions: Trauma, Nervous System.
What interventions are being tested in trial NCT00596609?
The interventions under investigation include: Intrathecal Morphine (DRUG).
Who is sponsoring clinical trial NCT00596609?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00596609 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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