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NCT00593840 · ClinicalTrials.gov registry record · Phase 2
Phase II Trial Evaluating Elimination of Radiation Therapy
A Phase 2 study of Cancer of the Larynx, sponsored by Washington University School of Medicine.
- Active
- Registry status
- Phase 2
- Development phase
- 74
- Enrollment target
- 1
- Study location
NCT00593840: Active Phase 2 study of Cancer of the Larynx, sponsored by Washington University School of Medicine.
NCT00593840 is a Phase 2 study of Cancer of the Larynx that is active but no longer recruiting, run by Washington University School of Medicine. The registered enrollment target is 74 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00593840, a Phase 2 study of Cancer of the Larynx, is active but no longer recruiting, sponsored by Washington University School of Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 74 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine if reducing or eliminating radiation treatment to one or both sides of the neck where there is no evidence of cancer can help spare the side effects of radiation treatment for head and neck cancer. In this study, the investigators plan to reduce the amount of radiation treatment received to healthy tissue
Primary Outcome
* Recurrence in a PN0 neck that was not treated is the critical endpoint in this study. * Recurrence is defined as the return of cancer after treatment * Recurrence is determined by a CT, PET/CT, or MRI and it will be fused with the original treatment planning CT scan. This will allow correlation between the original dose distribution and contours with any recurrent disease.
Conditions Studied
Interventions
- RADIATION Intensity modulated radiation therapy
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2007-04-11 |
| Est. Completion | 2026-04-30 |
| Phase | Phase 2 |
What the registry record for NCT00593840 still lists
NCT00593840 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 74 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% lower).
The record links to 1 condition, with Cancer of the Larynx appearing as the primary indexed condition, and to 1 intervention - of which Intensity modulated radiation therapy is the first listed.
NCT00593840 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT00593840 about?
NCT00593840 is a clinical study titled "Phase II Trial Evaluating Elimination of Radiation Therapy". The purpose of this study is to determine if reducing or eliminating radiation treatment to one or both sides of the neck where there is no evidence of cancer can help spare the side effects of radiation treatment for head and neck cancer. In this study, the investigators plan to reduce the amount o...
What is the current status of trial NCT00593840?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 74 participants. The study started on 2007-04-11. Estimated completion is 2026-04-30.
What conditions does trial NCT00593840 study?
This clinical trial studies the following conditions: Cancer of the Larynx.
What interventions are being tested in trial NCT00593840?
The interventions under investigation include: Intensity modulated radiation therapy (RADIATION).
Who is sponsoring clinical trial NCT00593840?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00593840 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cancer of the Larynx
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00593840's enrollment target sits among peer trials
74 920th of 2000 higher than 1,077 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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