Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00579774 · ClinicalTrials.gov registry record · NA
Effects of Glycoxidative Stress on Human Aging
A NA study, sponsored by Icahn School of Medicine at Mount Sinai.
- Completed
- Registry status
- NA
- Development phase
- 438
- Enrollment target
NCT00579774 is a NA study that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 438 participants.
The verdict
NCT00579774, a NA study, has completed, sponsored by Icahn School of Medicine at Mount Sinai.
- COMPLETED
- Registry status
- NA
- Development phase
- 438 participants
- Enrollment target
Study Summary
Advanced glycation products or AGEs are a heterogeneous group of molecules formed by exposure of tissue constituents to high levels of reducing sugars, e.g. glucose. The interaction of these compounds with extra- and intra-cellular components may account in part for several conditions related to aging. It has recently been recognized that AGEs are also formed during the preparation of food by heating, are absorbed into the circulation and become largely incorporated into tissue components. Accumulation of these exogenous substances over time may, together with those generated endogenously, contribute to the clinical manifestations and complications of aging. This is an interventional-randomized study in which we are trying to determine whether a diet low in AGE can effectively reduce circulating AGE levels, with or without altering oxidation or inflammatory markers, in a subset of both young and older subjects , over a period of 4 months. If positive results are obtained, longer-term prospective studies will be designed to determine if this intervention can affect disease outcomes in older age subjects. The study design is very simple and consists initially of obtaining a dietary history, a blood sample, 24-hour urine collection and, subsequently, of determining the effects of a low-AGE diet for 4 months on the plasma levels of these compounds in a group of healthy subjects.
Interventions
- OTHER Regular Diet
- OTHER Low AGE Diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 438 participants |
| Start Date | 2007-01 |
| Est. Completion | 2011-10 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00579774
The ClinicalTrials.gov registry entry for NCT00579774 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 438 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Icahn School of Medicine at Mount Sinai, which has 708 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Regular Diet is the first listed.
NCT00579774 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00579774 about?
NCT00579774 is a clinical study titled "Effects of Glycoxidative Stress on Human Aging". Advanced glycation products or AGEs are a heterogeneous group of molecules formed by exposure of tissue constituents to high levels of reducing sugars, e.g. glucose. The interaction of these compounds with extra- and intra-cellular components may account in part for several conditions related to agi...
What is the current status of trial NCT00579774?
This trial is currently completed. It is a NA study. The enrollment target is 438 participants. The study started on 2007-01. Estimated completion is 2011-10.
What interventions are being tested in trial NCT00579774?
The interventions under investigation include: Regular Diet (OTHER), Low AGE Diet (OTHER).
Who is sponsoring clinical trial NCT00579774?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.