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NCT00578422 · ClinicalTrials.gov registry record
Clinical Implications of Peripheral Plaque Morphology
A clinical trial, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- 143
- Enrollment target
NCT00578422: Completed study, sponsored by The Cleveland Clinic.
NCT00578422 is a clinical trial that has completed, run by The Cleveland Clinic. The registered enrollment target is 143 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00578422 has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- 143 participants
- Enrollment target
Study Summary
Peripheral Artery Disease involves a buildup of fatty deposits (plaque) within blood vessels that can restrict blood flow. Patients who have PAD and claudication (pain in legs during exercise due to poor blood circulation) may be eligible for this clinical trial. Three primary hypotheses will be tested in this study: (1) IVUS (Intravascular Ultrasound)combined with advanced digital image and signal processing provides a sensitive method to determine plaque geometry and composition in the human peripheral artery wall; (2) IVUS can discern specific arterial wall morphology, providing data that can be used to identify plaques that predispose the patient to late complications; and (3) IVUS-derived plaque structure can be used to predict responders and non-responders to pharmacologic therapy and percutaneous endovascular interventions. These hypotheses will be tested as follows: (1) custom engineered IVUS analysis software will be used to describe the geometry, composition, and spatial component relationships of the vessel, (2) the morphology of lower extremity arterial plaque, as determined by IVUS, will be correlated with baseline clinical characteristics of subjects, and (3) the effects on plaque morphology after long term treatment with antihyperlipidemics will be determined.
Primary Outcome
Spectral analysis of plaque
Interventions
- OTHER Ivus (Intravascular Ultrasound) of Amputation Specimens
- PROCEDURE IVUS (Intravascular Ultrasound)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 143 participants |
| Start Date | 2003-12 |
| Est. Completion | 2016-11 |
What the finished NCT00578422 record still lists
NCT00578422 is an observational study that tracks outcomes without assigning an intervention. The registered 143 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 2 interventions - of which Ivus (Intravascular Ultrasound) of Amputation Specimens is the first listed.
NCT00578422 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00578422 about?
NCT00578422 is a clinical study titled "Clinical Implications of Peripheral Plaque Morphology". Peripheral Artery Disease involves a buildup of fatty deposits (plaque) within blood vessels that can restrict blood flow. Patients who have PAD and claudication (pain in legs during exercise due to poor blood circulation) may be eligible for this clinical trial. Three primary hypotheses will be tes...
What is the current status of trial NCT00578422?
This trial is currently completed. The enrollment target is 143 participants. The study started on 2003-12. Estimated completion is 2016-11.
What interventions are being tested in trial NCT00578422?
The interventions under investigation include: Ivus (Intravascular Ultrasound) of Amputation Specimens (OTHER), IVUS (Intravascular Ultrasound) (PROCEDURE).
Who is sponsoring clinical trial NCT00578422?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
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