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NCT00571662 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy of Pentostatin and Low Dose TBI With Allogenic Peripheral Blood Stem Cell Transplant
A Phase 2 study, sponsored by University of Nebraska.
- Completed
- Registry status
- Phase 2
- Development phase
- 76
- Enrollment target
NCT00571662: Completed Phase 2 study, sponsored by University of Nebraska.
NCT00571662 is a Phase 2 study that has completed, run by University of Nebraska. The registered enrollment target is 76 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00571662, a Phase 2 study, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 76 participants
- Enrollment target
Study Summary
This is a continuation of a pilot study which is now regarded as a phase II trial with a plan to enroll an additional 40 patients (20 related and 20 unrelated donor transplants) with hematological malignancy assessing the safety and efficacy of a minimally myelosuppressive regimen with pentostatin and low-dose total body irradiation (TBI) followed by allogeneic peripheral blood stem cell transplantation (alloPSCT).
Primary Outcome
the efficacy of the regimen as determined by engraftment rate and establishment of donor hematopoietic chimerism at day +28 and day +70.
Interventions
- DRUG G-CSF
- DRUG Mycophenolate Mofetil (MMF)
- DRUG Pentostatin
- RADIATION Total-body irradiation (TBI)
- DRUG Cyclosporine A (CsA)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2000-12-08 |
| Est. Completion | 2008-12-30 |
| Phase | Phase 2 |
What the finished NCT00571662 record still lists
NCT00571662 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (43% lower).
The record links to 0 conditions, and to 5 interventions - of which G-CSF is the first listed.
NCT00571662 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00571662 about?
NCT00571662 is a clinical study titled "Safety and Efficacy of Pentostatin and Low Dose TBI With Allogenic Peripheral Blood Stem Cell Transplant". This is a continuation of a pilot study which is now regarded as a phase II trial with a plan to enroll an additional 40 patients (20 related and 20 unrelated donor transplants) with hematological malignancy assessing the safety and efficacy of a minimally myelosuppressive regimen with pentostatin a...
What is the current status of trial NCT00571662?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 76 participants. The study started on 2000-12-08. Estimated completion is 2008-12-30.
What interventions are being tested in trial NCT00571662?
The interventions under investigation include: G-CSF (DRUG), Mycophenolate Mofetil (MMF) (DRUG), Pentostatin (DRUG), Total-body irradiation (TBI) (RADIATION), Cyclosporine A (CsA) (DRUG).
Who is sponsoring clinical trial NCT00571662?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00571662's enrollment target sits among peer trials
76 893rd of 2000 higher than 1,101 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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