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NCT00567242 · ClinicalTrials.gov registry record · Phase 1
Treating Intention In Aphasia: Neuroplastic Substrates
A Phase 1 study, sponsored by University of Florida.
- Completed
- Registry status
- Phase 1
- Development phase
- 14
- Enrollment target
NCT00567242: Completed Phase 1 study, sponsored by University of Florida.
NCT00567242 is a Phase 1 study that has completed, run by University of Florida. The registered enrollment target is 14 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00567242, a Phase 1 study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 14 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if an "intentional act" improves treatment response for patients with nonfluent aphasia. The treatment involves naming pictures and saying members of categories. The "intentional act" requires initiating picture naming or category member trials with a left-hand movement sequence. Nonfluent aphasia is a disorder of language production in which patients with damage to the brain's language system have trouble initiating and maintaining spoken communication. All patients participating in the study take part in functional MRI scans to determine how treatments affect brain systems.
Primary Outcome
Functional MRI laterality indices (LIs)were calculated for lateral frontal, medial frontal, and posterior perisylvian cortex regions of interest (ROIs): L=number of active voxels in left hemisphere ROI and R=number of active voxels in right hemisphere ROI using the following formula: (L-R)/(L+R). LIs could vary from -1 (completely right lateralized) to +1 (completely left lateralized). Then, change in LIs was calculated by subtracting the pre-treatment from the post-treatment and 3-mo follow-up
Interventions
- BEHAVIORAL Word-finding with intention component
- BEHAVIORAL Word-finding with no intention component
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2007-03 |
| Est. Completion | 2009-09 |
| Phase | Phase 1 |
What the finished NCT00567242 record still lists
NCT00567242 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 2 interventions - of which Word-finding with intention component is the first listed.
NCT00567242 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00567242 about?
NCT00567242 is a clinical study titled "Treating Intention In Aphasia: Neuroplastic Substrates". The purpose of this study is to determine if an "intentional act" improves treatment response for patients with nonfluent aphasia. The treatment involves naming pictures and saying members of categories. The "intentional act" requires initiating picture naming or category member trials with a left-h...
What is the current status of trial NCT00567242?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2007-03. Estimated completion is 2009-09.
What interventions are being tested in trial NCT00567242?
The interventions under investigation include: Word-finding with intention component (BEHAVIORAL), Word-finding with no intention component (BEHAVIORAL).
Who is sponsoring clinical trial NCT00567242?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00567242's enrollment target sits among peer trials
14 1844th of 2000 higher than 154 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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