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NCT00565617 · ClinicalTrials.gov registry record · NA
Epidural Cortical Stimulation for Depression
A NA study of Treatment-Resistant Depression, sponsored by Medical University of South Carolina.
- Active
- Registry status
- NA
- Development phase
- 5
- Enrollment target
- 1
- Study location
NCT00565617: Active NA study of Treatment-Resistant Depression, sponsored by Medical University of South Carolina.
NCT00565617 is a NA study of Treatment-Resistant Depression that is active but no longer recruiting, run by Medical University of South Carolina. The registered enrollment target is 5 participants, below the 374-participant average among 54 other Treatment-Resistant Depression trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00565617, a NA study of Treatment-Resistant Depression, is active but no longer recruiting, sponsored by Medical University of South Carolina.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
- 1
- Study location
Study Summary
Objective: Chronic epidural cortical stimulation (ECS) involves the neurosurgical placement of an electric wire on the surface of the brain with intermittent activation. Over time, ECS modulates local and distal connected brain regions. It is being currently applied over the motor cortex to treat intractable pain. Because of the important role played by the medial prefrontal cortex in mood regulation, the goal of this study is to apply this minimally invasive neurostimulation modality over medial prefrontal cortex in severely ill depressed subjects who have failed all other attempts at treatment.
Primary Outcome
Hamilton Depression Rating Scale (HDRS) is a standard, validated depression rating scale. It is a 24 item scale, but the primary score is based on the first 17 answers for a total score for depression. 0-7=Normal 8 - 13 = Mild Depression 14-18 = Moderate Depression 19 - 22 = Severe Depression \> 23 = Very Severe Depression
Conditions Studied
Interventions
- DEVICE Synergy, Epidural cortical stimulation
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2007-10 |
| Est. Completion | 2028-12 |
| Phase | NA |
What the registry record for NCT00565617 still lists
NCT00565617 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 374-participant average among 54 other Treatment-Resistant Depression trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Treatment-Resistant Depression appearing as the primary indexed condition, and to 1 intervention - of which Synergy, Epidural cortical stimulation is the first listed.
NCT00565617 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT00565617 about?
NCT00565617 is a clinical study titled "Epidural Cortical Stimulation for Depression". Objective: Chronic epidural cortical stimulation (ECS) involves the neurosurgical placement of an electric wire on the surface of the brain with intermittent activation. Over time, ECS modulates local and distal connected brain regions. It is being currently applied over the motor cortex to treat in...
What is the current status of trial NCT00565617?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 5 participants. The study started on 2007-10. Estimated completion is 2028-12.
What conditions does trial NCT00565617 study?
This clinical trial studies the following conditions: Treatment-Resistant Depression.
What interventions are being tested in trial NCT00565617?
The interventions under investigation include: Synergy, Epidural cortical stimulation (DEVICE).
Who is sponsoring clinical trial NCT00565617?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00565617 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Treatment-Resistant Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00565617's enrollment target sits among peer trials
5 54th of 54 higher than 1 of 54 other Treatment-Resistant Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Treatment-Resistant Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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