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NCT00560391 · ClinicalTrials.gov registry record · Phase 1

Dasatinib in Combination With Revlimid (and Dexamethasone)

A Phase 1 study of Multiple Myeloma, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 1
Development phase
35
Enrollment target
4
Study locations

NCT00560391 is a Phase 1 study of Multiple Myeloma that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 35 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (94% lower). The trial reports 4 study locations across 3 states.

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The verdict

NCT00560391, a Phase 1 study of Multiple Myeloma, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 1
Development phase
35 participants
Enrollment target
4
Study locations

Study Summary

The purpose of this study was to determine the safety and tolerability of dasatinib when given in combination with lenalidomide and a low dose dexamethasone for the treatment of relapsed or refractory multiple myeloma.

Conditions Studied

Interventions

  • DRUG Dasatinib, 70 mg + Lenalidomide, 15 mg + Dexamethasone, 40 mg
  • DRUG Dasatinib, 70 mg + Lenalidomide, 20 mg + Dexamethasone, 40 mg
  • DRUG Dasatinib, 100 mg + Lenalidomide, 20 mg + Dexamethasone, 40 mg
  • DRUG Dasatinib, 100 mg + Lenalidomide, 25 mg + Dexamethasone, 40 mg
  • DRUG Dasatinib, 140 mg + Lenalidomide, 25 mg + Dexamethasone, 40 mg

Study Locations (4)

Other

  • Local Institution - Toulouse
  • Local Institution - Vandœuvre-lès-Nancy

Arizona

  • Mayo Clinic Arizona - Scottsdale

Victoria

  • Local Institution - Prahran

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2008-05
Est. Completion 2012-11
Phase Phase 1

Sponsor

Bristol-Myers Squibb

1,025 total trials

What the Registry Record Tells You About NCT00560391

The ClinicalTrials.gov registry entry for NCT00560391 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (94% lower). The listed sponsor is Bristol-Myers Squibb, which has 1,025 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 5 interventions - of which Dasatinib, 70 mg + Lenalidomide, 15 mg + Dexamethasone, 40 mg is the first listed.

NCT00560391 reports 4 study locations spanning 3 distinct geographic areas - top geographies include Other, Arizona, Victoria.

Frequently Asked Questions

What is clinical trial NCT00560391 about?

NCT00560391 is a clinical study titled "Dasatinib in Combination With Revlimid (and Dexamethasone)". The purpose of this study was to determine the safety and tolerability of dasatinib when given in combination with lenalidomide and a low dose dexamethasone for the treatment of relapsed or refractory multiple myeloma.

What is the current status of trial NCT00560391?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 35 participants. The study started on 2008-05. Estimated completion is 2012-11.

What conditions does trial NCT00560391 study?

This clinical trial studies the following conditions: Multiple Myeloma.

What interventions are being tested in trial NCT00560391?

The interventions under investigation include: Dasatinib, 70 mg + Lenalidomide, 15 mg + Dexamethasone, 40 mg (DRUG), Dasatinib, 70 mg + Lenalidomide, 20 mg + Dexamethasone, 40 mg (DRUG), Dasatinib, 100 mg + Lenalidomide, 20 mg + Dexamethasone, 40 mg (DRUG), Dasatinib, 100 mg + Lenalidomide, 25 mg + Dexamethasone, 40 mg (DRUG), Dasatinib, 140 mg + Lenalidomide, 25 mg + Dexamethasone, 40 mg (DRUG).

Who is sponsoring clinical trial NCT00560391?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00560391 being conducted?

This trial has 4 study locations across Arizona, Victoria. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.