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NCT00555906 · ClinicalTrials.gov registry record · Phase 2

An Investigational Drug, Palbociclib (PD-0332991), Is Being Studied In Combination With Velcade And Dexamethasone In Patients With Multiple Myeloma. Patients Must Have Received Prior Treatment For Multiple Myeloma.

A Phase 2 study of Multiple Myeloma, sponsored by Pfizer.

Completed
Registry status
Phase 2
Development phase
53
Enrollment target
19
Study locations

NCT00555906 is a Phase 2 study of Multiple Myeloma that has completed, run by Pfizer. The registered enrollment target is 53 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (90% lower). The trial reports 19 study locations across 10 states.

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The verdict

NCT00555906, a Phase 2 study of Multiple Myeloma, has completed, sponsored by Pfizer.

COMPLETED
Registry status
Phase 2
Development phase
53 participants
Enrollment target
19
Study locations

Study Summary

This is a Phase 1/2 study evaluating the safety and anti-tumor activity of PD 0332991 in combination with Velcade® \[bortezomib\] and dexamethasone in patients who have received at least one previous treatment for multiple myeloma.

Conditions Studied

Interventions

  • DRUG Dexamethasone
  • DRUG Bortezomib
  • DRUG PD 0332991

Study Locations (19)

Missouri

  • Washington University School of Medicine - St Louis
  • Barnes-Jewish Hospital - St Louis
  • Washington University School of Medicine - St Louis

Other

  • Vseobecna fakultni nemocnice v Praze - Prague
  • Universitaetsklinikum Heidelberg - Heidelberg
  • Klinikum Johannes-Gutenberg -Universitaet, III. Medizinische Klinik und Poliklinik - Mainz

Illinois

  • Northwestern Medical Faculty Foundation - Chicago
  • Northwestern Memorial Hospital/Main Labs - Chicago

Kansas

  • University of Kansas Medical Center - Kansas City
  • University of Kansas Cancer Center and Medical Pavilion - Westwood

New York

  • Roswell Park Cancer Institute - Buffalo
  • New York Presbyterian, Weill Cornell Medical College - New York

Pennsylvania

  • University of Pennsylvania Abramson Cancer Center - Philadelphia
  • University of Pittsburgh Cancer Institute - Pittsburgh

South Carolina

  • Hollings Cancer Center - Charleston
  • Medical University of South Carolina - Charleston

Maryland

  • University of Maryland - Baltimore

Trial Details

FieldValue
Enrollment Target 53 participants
Start Date 2008-01
Est. Completion 2013-03
Phase Phase 2

Sponsor

Pfizer

1,845 total trials

What the Registry Record Tells You About NCT00555906

The ClinicalTrials.gov registry entry for NCT00555906 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 53 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (90% lower). The listed sponsor is Pfizer, which has 1,845 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 3 interventions - of which Dexamethasone is the first listed.

NCT00555906 reports 19 study locations spanning 10 distinct geographic areas - top geographies include Missouri, Other, Illinois.

Frequently Asked Questions

What is clinical trial NCT00555906 about?

NCT00555906 is a clinical study titled "An Investigational Drug, Palbociclib (PD-0332991), Is Being Studied In Combination With Velcade And Dexamethasone In Patients With Multiple Myeloma. Patients Must Have Received Prior Treatment For Multiple Myeloma.". This is a Phase 1/2 study evaluating the safety and anti-tumor activity of PD 0332991 in combination with Velcade® \[bortezomib\] and dexamethasone in patients who have received at least one previous treatment for multiple myeloma.

What is the current status of trial NCT00555906?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 53 participants. The study started on 2008-01. Estimated completion is 2013-03.

What conditions does trial NCT00555906 study?

This clinical trial studies the following conditions: Multiple Myeloma.

What interventions are being tested in trial NCT00555906?

The interventions under investigation include: Dexamethasone (DRUG), Bortezomib (DRUG), PD 0332991 (DRUG).

Who is sponsoring clinical trial NCT00555906?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00555906 being conducted?

This trial has 19 study locations across Illinois, Kansas, Maryland, Michigan, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.