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NCT00553384 · ClinicalTrials.gov registry record

Physiological Effects of Androstadienone Exposure

A clinical trial of Healthy, sponsored by Rockefeller University.

Completed
Registry status
68
Enrollment target
1
Study location

NCT00553384: Completed study of Healthy, sponsored by Rockefeller University.

NCT00553384 is a study of Healthy that has completed, run by Rockefeller University. The registered enrollment target is 68 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00553384, a study of Healthy, has completed, sponsored by Rockefeller University.

COMPLETED
Registry status
68 participants
Enrollment target
1
Study location

Study Summary

The reason for doing this research is to understand why different people show different responses when they smell an odor called androstadienone. Androstadienone is a chemical found in male sweat. Other studies have shown that smelling this chemical can cause people to experience sweating, changes in skin temperature, and changes in a stress hormone call cortisol. These responses, which are called "physiological effects," are stronger in some people than in others. We are interested in finding out whether these individual differences are genetic, that is caused by differences in our genes. Humans have about 1000 genes for odorant receptors. These are the molecules that bind and detect odor molecules in our nose and allow us to respond to so many different odors. It has been shown that some of these genes exist in two forms: a functional one and one that has been mutated and is therefore no longer functional. We think that people who do not respond to a specific odor may carry the non-functional form of the gene for the receptor that detects the odor molecule. To test this idea we want to find people who respond strongly to a specific smell, and compare their odorant receptor genes with those of people who respond weakly to the odor.

Conditions Studied

Study Locations (1)

New York

  • The Rockefeller University Hospital - New York

Trial Details

FieldValue
Enrollment Target 68 participants
Start Date 2007-12
Est. Completion 2010-07
Rockefeller University

117 total trials

What the finished NCT00553384 record still lists

NCT00553384 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (89% lower).

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 0 interventions.

NCT00553384 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT00553384 about?

NCT00553384 is a clinical study titled "Physiological Effects of Androstadienone Exposure". The reason for doing this research is to understand why different people show different responses when they smell an odor called androstadienone. Androstadienone is a chemical found in male sweat. Other studies have shown that smelling this chemical can cause people to experience sweating, changes i...

What is the current status of trial NCT00553384?

This trial is currently completed. The enrollment target is 68 participants. The study started on 2007-12. Estimated completion is 2010-07.

What conditions does trial NCT00553384 study?

This clinical trial studies the following conditions: Healthy.

Who is sponsoring clinical trial NCT00553384?

This trial is sponsored by Rockefeller University, which has 117 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00553384 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00553384's enrollment target sits among peer trials

68 335th of 1090 higher than 751 of 1,090 other Healthy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00553384, the US trial registry maintained by the National Library of Medicine. NCT00553384 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.