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NCT00544804 · ClinicalTrials.gov registry record · Phase 1

Lapatinib in Treating Patients With Advanced or Metastatic Breast Cancer That Overexpresses HER2

A Phase 1 study of Breast Cancer and Metastatic Cancer, sponsored by University of California, San Francisco.

Completed
Registry status
Phase 1
Development phase
41
Enrollment target
1
Study location

NCT00544804 is a Phase 1 study of Breast Cancer and Metastatic Cancer that has completed, run by University of California, San Francisco. The registered enrollment target is 41 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00544804, a Phase 1 study of Breast Cancer and Metastatic Cancer, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 1
Development phase
41 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Lapatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I trial is studying the side effects and best dose of lapatinib in treating patients with advanced or metastatic breast cancer that overexpresses HER2.

Interventions

  • GENETIC gene expression analysis
  • OTHER diagnostic laboratory biomarker analysis
  • DRUG lapatinib ditosylate

Study Locations (1)

California

  • UCSF Helen Diller Family Comprehensive Cancer Center - San Francisco

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2007-08
Est. Completion 2013-12
Phase Phase 1

What the Registry Record Tells You About NCT00544804

The ClinicalTrials.gov registry entry for NCT00544804 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 3 interventions - of which gene expression analysis is the first listed.

NCT00544804 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT00544804 about?

NCT00544804 is a clinical study titled "Lapatinib in Treating Patients With Advanced or Metastatic Breast Cancer That Overexpresses HER2". RATIONALE: Lapatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I trial is studying the side effects and best dose of lapatinib in treating patients with advanced or metastatic breast cancer that overexpresses HER2.

What is the current status of trial NCT00544804?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2007-08. Estimated completion is 2013-12.

What conditions does trial NCT00544804 study?

This clinical trial studies the following conditions: Breast Cancer, Metastatic Cancer.

What interventions are being tested in trial NCT00544804?

The interventions under investigation include: gene expression analysis (GENETIC), diagnostic laboratory biomarker analysis (OTHER), lapatinib ditosylate (DRUG).

Who is sponsoring clinical trial NCT00544804?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00544804 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.