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NCT00524472 · ClinicalTrials.gov registry record · NA
Outcomes Study of Hyperinsulinemic Glucose Control in Cardiac Surgery
A NA study, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- NA
- Development phase
- 1,439
- Enrollment target
NCT00524472: Completed NA study, sponsored by The Cleveland Clinic.
NCT00524472 is a NA study that has completed, run by The Cleveland Clinic. The registered enrollment target is 1,439 participants, roughly in line with the 1,404-participant average among 58,714 other NA trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00524472, a NA study, has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 1,439 participants
- Enrollment target
Study Summary
Patients undergoing cardiac surgery will be randomized into one of two groups. Group A will be administered insulin using the hyperinsulinemic-normoglycemic clamp to normalize blood glucose levels intra-operatively. Group B will be administered insulin at the standard of care levels established by the participating institution. Patients will be followed at 10 days, 15 days and one year post-operatively.
Primary Outcome
a composite (any versus none) of the following major postoperative complications occurring: 1. all-cause postoperative mortality 2. failure to wean from cardiopulmonary bypass or postoperative low cardiac index requiring mechanical circulatory support with intraaortic balloon counterpulsation, ventricular assist device, and/or extracorporeal mechanical oxygenation 3. serious postoperative infection 4. acute postoperative kidney injury requiring renal replacement therapy; 5. new postoperative fo
Interventions
- OTHER Hyperinsulinemic-normoglycemic clamp
- OTHER insulin at the standard of care levels
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,439 participants |
| Start Date | 2007-07 |
| Est. Completion | 2015-04 |
| Phase | NA |
What the finished NCT00524472 record still lists
NCT00524472 is an interventional study that assigns participants to a tested intervention. Its 1,439 participants enrollment target places it among the larger protocols in the corpus, roughly in line with the 1,404-participant average among 58,714 other NA trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Hyperinsulinemic-normoglycemic clamp is the first listed.
NCT00524472 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00524472 about?
NCT00524472 is a clinical study titled "Outcomes Study of Hyperinsulinemic Glucose Control in Cardiac Surgery". Patients undergoing cardiac surgery will be randomized into one of two groups. Group A will be administered insulin using the hyperinsulinemic-normoglycemic clamp to normalize blood glucose levels intra-operatively. Group B will be administered insulin at the standard of care levels established by t...
What is the current status of trial NCT00524472?
This trial is currently completed. It is a NA study. The enrollment target is 1,439 participants. The study started on 2007-07. Estimated completion is 2015-04.
What interventions are being tested in trial NCT00524472?
The interventions under investigation include: Hyperinsulinemic-normoglycemic clamp (OTHER), insulin at the standard of care levels (OTHER).
Who is sponsoring clinical trial NCT00524472?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00524472's enrollment target sits among peer trials
1,439 70th of 2000 higher than 1,931 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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