Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00511095 · ClinicalTrials.gov registry record · Phase 2

Open-Label Study of the Safety and Immunogenicity of HEPLISAV™ Hepatitis B Virus Vaccine

A Phase 2 study, sponsored by Dynavax Technologies Corporation.

Completed
Registry status
Phase 2
Development phase
207
Enrollment target

NCT00511095: Completed Phase 2 study, sponsored by Dynavax Technologies Corporation.

NCT00511095 is a Phase 2 study that has completed, run by Dynavax Technologies Corporation. The registered enrollment target is 207 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (56% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00511095, a Phase 2 study, has completed, sponsored by Dynavax Technologies Corporation.

COMPLETED
Registry status
Phase 2
Development phase
207 participants
Enrollment target

Study Summary

The purpose of this study is to further evaluate the safety and seroprotective immune response of a new investigational hepatitis B virus (HBV) vaccine, HEPLISAV™, in subjects 11-55 years old. The primary hypothesis is that HEPLISAV™ is well tolerated.

Primary Outcome

Local and Systemic post-injection reactions.

Interventions

  • BIOLOGICAL HEPLISAV

Trial Details

FieldValue
Enrollment Target 207 participants
Start Date 2007-06
Est. Completion 2008-03
Phase Phase 2
Dynavax Technologies Corporation

16 total trials

What the finished NCT00511095 record still lists

NCT00511095 is an interventional study that assigns participants to a tested intervention. The registered 207 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (56% higher).

The record links to 0 conditions, and to 1 intervention - of which HEPLISAV is the first listed.

NCT00511095 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00511095 about?

NCT00511095 is a clinical study titled "Open-Label Study of the Safety and Immunogenicity of HEPLISAV™ Hepatitis B Virus Vaccine". The purpose of this study is to further evaluate the safety and seroprotective immune response of a new investigational hepatitis B virus (HBV) vaccine, HEPLISAV™, in subjects 11-55 years old. The primary hypothesis is that HEPLISAV™ is well tolerated.

What is the current status of trial NCT00511095?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 207 participants. The study started on 2007-06. Estimated completion is 2008-03.

What interventions are being tested in trial NCT00511095?

The interventions under investigation include: HEPLISAV (BIOLOGICAL).

Who is sponsoring clinical trial NCT00511095?

This trial is sponsored by Dynavax Technologies Corporation, which has 16 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00511095's enrollment target sits among peer trials

207 297th of 2000 higher than 1,703 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04353778 · 207 participants · Phase 1

    Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV

  • NCT05875805 · 207 participants · NA

    A Telehealth Advance Care Planning Intervention

  • NCT06254950 · 207 participants · Phase 2

    A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

  • NCT06904274 · 207 participants · Phase 3

    Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00511095, the US trial registry maintained by the National Library of Medicine. NCT00511095 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.