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NCT00505297 · ClinicalTrials.gov registry record
A Longitudinal Study of Osteoarthritis (OA) Disease Progression Measured by MRI, dGEMRIC, and Radiography
A clinical trial of Osteoarthritis, sponsored by University of California, San Francisco.
- Completed
- Registry status
- 18
- Enrollment target
- 1
- Study location
NCT00505297: Completed study of Osteoarthritis, sponsored by University of California, San Francisco.
NCT00505297 is a study of Osteoarthritis that has completed, run by University of California, San Francisco. The registered enrollment target is 18 participants, below the 818-participant average among 135 other Osteoarthritis trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00505297, a study of Osteoarthritis, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
In order to design future disease modifying osteoarthritis drug (DMOAD) proof of concept studies, this study is being conducted to assess magnetic resonance imaging (MRI) measurements of cartilage morphology and glycosaminoglycan (GAG) content as it relates to the progression of disease in subjects with potentially rapidly progressing OA. The subject population is selected to have higher likelihood of having rapidly progressing OA (i.e., a more rapid joint space narrowing (JSN) compared to general knee OA population and thus, may be more likely to have changes in GAG content and/or cartilage volume. The results of this study may provide a reasonable means to assess DMOAD activity of drugs in development. The non-OA controls are included to determine the rate of change for subjects of similar age. Ideally, results of this study will identify reliable methods for delayed Gadolinium Enhanced MRI of cartilage (dGEMRIC) and MRI cartilage assessment that correlate with OA disease progression as compared to x-ray changes.
Conditions Studied
Study Locations (1)
California
- University of California - San Frnacisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2004-08 |
| Est. Completion | 2007-07 |
What the finished NCT00505297 record still lists
NCT00505297 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 818-participant average among 135 other Osteoarthritis trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Osteoarthritis appearing as the primary indexed condition, and to 0 interventions.
NCT00505297 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00505297 about?
NCT00505297 is a clinical study titled "A Longitudinal Study of Osteoarthritis (OA) Disease Progression Measured by MRI, dGEMRIC, and Radiography". In order to design future disease modifying osteoarthritis drug (DMOAD) proof of concept studies, this study is being conducted to assess magnetic resonance imaging (MRI) measurements of cartilage morphology and glycosaminoglycan (GAG) content as it relates to the progression of disease in subjects ...
What is the current status of trial NCT00505297?
This trial is currently completed. The enrollment target is 18 participants. The study started on 2004-08. Estimated completion is 2007-07.
What conditions does trial NCT00505297 study?
This clinical trial studies the following conditions: Osteoarthritis.
Who is sponsoring clinical trial NCT00505297?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00505297 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00505297's enrollment target sits among peer trials
18 135th of 135 higher than 1 of 135 other Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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