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NCT00504049 · ClinicalTrials.gov registry record

Wavelet Analysis of Electromyography (EMG) in Cerebral Palsy

A clinical trial of Cerebral Palsy, sponsored by Shriners Hospitals for Children.

Completed
Registry status
32
Enrollment target
1
Study location

NCT00504049 is a study of Cerebral Palsy that has completed, run by Shriners Hospitals for Children. The registered enrollment target is 32 participants, below the 229-participant average among 91 other Cerebral Palsy trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00504049, a study of Cerebral Palsy, has completed, sponsored by Shriners Hospitals for Children.

COMPLETED
Registry status
32 participants
Enrollment target
1
Study location

Study Summary

Several methods exist to evaluate motor function in the child with cerebral palsy and are used to assess the outcome of a clinical intervention. However, these scales are not directed towards measuring the changes in muscle activity patterns that can result from the intervention. For example, there are classification scales aimed at measuring motor function and functional abilities, and indices of gait function. These scores, while providing a way to quantify function and mechanics, do not directly measure muscle activation characteristics. Therefore, these tests may be insensitive to how the intervention has directly affected muscle function, which is usually the focus of the intervention (i.e. botulinum toxin, functional electrical stimulation, dorsal rhizotomy). Muscle biopsies and motor evoked potentials can provide information about the muscle activation characteristics, however, they are invasive and there are concerns about using these techniques on the pediatric population and/or the practicality of clinical implementation, especially since they do not provide insight into how the muscle behaves during a functional task. One method that can be used to provide insight into muscle activity in a non-invasive and clinically meaningful manner is the use of surface electromyography (sEMG). Surface EMG is typically a routine part of clinical assessment and the evaluation of motor impairment in CP. However, the analysis of the data has been limited in most cases to examination of signal amplitude or differences in muscle onset and offset timing. The long-term goal of this research is to develop an analysis method for sEMG that can be used during functional tasks for treatment planning, diagnostic, assessment purposes in CP. This is to be accomplished through the use of the continuous wavelet transform (CWT). By developing an assessment method based on muscle activity, it is believed that a clinically viable measurement tool can be devised that will provide a level

Conditions Studied

Study Locations (1)

Pennsylvania

  • Shriners Hospitals for Children - Philadelphia

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2007-03
Est. Completion 2009-03

Sponsor

Shriners Hospitals for Children

40 total trials

What the Registry Record Tells You About NCT00504049

The ClinicalTrials.gov registry entry for NCT00504049 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 229-participant average among 91 other Cerebral Palsy trials with a reported enrollment target (86% lower). The listed sponsor is Shriners Hospitals for Children, which has 40 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cerebral Palsy appearing as the primary indexed condition, and to 0 interventions.

NCT00504049 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT00504049 about?

NCT00504049 is a clinical study titled "Wavelet Analysis of Electromyography (EMG) in Cerebral Palsy". Several methods exist to evaluate motor function in the child with cerebral palsy and are used to assess the outcome of a clinical intervention. However, these scales are not directed towards measuring the changes in muscle activity patterns that can result from the intervention. For example, there ...

What is the current status of trial NCT00504049?

This trial is currently completed. The enrollment target is 32 participants. The study started on 2007-03. Estimated completion is 2009-03.

What conditions does trial NCT00504049 study?

This clinical trial studies the following conditions: Cerebral Palsy.

Who is sponsoring clinical trial NCT00504049?

This trial is sponsored by Shriners Hospitals for Children, which has 40 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00504049 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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