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NCT00494494 · ClinicalTrials.gov registry record · Phase 4

Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery

A Phase 4 study, sponsored by University of North Carolina, Chapel Hill.

Completed
Registry status
Phase 4
Development phase
82
Enrollment target

NCT00494494 is a Phase 4 study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 82 participants.

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The verdict

NCT00494494, a Phase 4 study, has completed, sponsored by University of North Carolina, Chapel Hill.

COMPLETED
Registry status
Phase 4
Development phase
82 participants
Enrollment target

Study Summary

Purpose: Study the effect of nepafenac ophthalmic suspension 0.1% to prevent post-operative cystoid macular edema following uncomplicated cataract surgery Participants: Patients having cataract surgery at UNC who meet eligibility criteria Procedures (methods): Patients will have pre and post-operative vision measured and optical coherence tomography (OCT) testing, also cataract density and intraoperative phacoemulsification parameters including ultrasound power and ultrasound time will be measured. Patients will be randomized into two groups. Group 1 will be treated with standard post-operative cataract management. Group 2 will be treated with standard post-operative cataract management plus topical nepafenac for one month. Post-operative macular thickness will be studied by analyzing the visual acuity and OCT measurements at two months post surgery.

Interventions

  • DRUG Standard Care
  • DRUG nepafenac

Trial Details

FieldValue
Enrollment Target 82 participants
Start Date 2007-06
Est. Completion 2008-04
Phase Phase 4

What the Registry Record Tells You About NCT00494494

The ClinicalTrials.gov registry entry for NCT00494494 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 82 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Standard Care is the first listed.

NCT00494494 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00494494 about?

NCT00494494 is a clinical study titled "Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery". Purpose: Study the effect of nepafenac ophthalmic suspension 0.1% to prevent post-operative cystoid macular edema following uncomplicated cataract surgery Participants: Patients having cataract surgery at UNC who meet eligibility criteria Procedures (methods): Patients will have pre and post-opera...

What is the current status of trial NCT00494494?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 82 participants. The study started on 2007-06. Estimated completion is 2008-04.

What interventions are being tested in trial NCT00494494?

The interventions under investigation include: Standard Care (DRUG), nepafenac (DRUG).

Who is sponsoring clinical trial NCT00494494?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.