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NCT00460707 · ClinicalTrials.gov registry record · Phase 1
A Study to Assess the Safety and Interaction Between Casopitant and Ketoconazole When Taken By Healthy Adults
A Phase 1 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 1
- Development phase
- 85
- Enrollment target
NCT00460707: Completed Phase 1 study, sponsored by GlaxoSmithKline.
NCT00460707 is a Phase 1 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 85 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (42% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00460707, a Phase 1 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 85 participants
- Enrollment target
Study Summary
Casopitant may affect liver enzymes that metabolize ketoconazole. This study is designed to test the safety and the extent of the Casopitant affect on ketoconazole levels in healthy human subjects.
Interventions
- DRUG Ketoconazole
- DRUG Casopitant 50 mg
- DRUG Casopitant 150 mg
- DRUG Casopitant 150 mg matching placebo
- DRUG Casopitant 50 mg matching placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 85 participants |
| Start Date | 2007-04-16 |
| Est. Completion | 2007-08-27 |
| Phase | Phase 1 |
What the finished NCT00460707 record still lists
NCT00460707 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 85 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (42% higher).
The record links to 0 conditions, and to 5 interventions - of which Ketoconazole is the first listed.
NCT00460707 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00460707 about?
NCT00460707 is a clinical study titled "A Study to Assess the Safety and Interaction Between Casopitant and Ketoconazole When Taken By Healthy Adults". Casopitant may affect liver enzymes that metabolize ketoconazole. This study is designed to test the safety and the extent of the Casopitant affect on ketoconazole levels in healthy human subjects.
What is the current status of trial NCT00460707?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 85 participants. The study started on 2007-04-16. Estimated completion is 2007-08-27.
What interventions are being tested in trial NCT00460707?
The interventions under investigation include: Ketoconazole (DRUG), Casopitant 50 mg (DRUG), Casopitant 150 mg (DRUG), Casopitant 150 mg matching placebo (DRUG), Casopitant 50 mg matching placebo (DRUG).
Who is sponsoring clinical trial NCT00460707?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00460707's enrollment target sits among peer trials
85 656th of 2000 higher than 1,342 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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