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NCT00457847 · ClinicalTrials.gov registry record
Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation
A clinical trial of Lung Transplantation and Primary Graft Dysfunction, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- 1,150
- Enrollment target
- 1
- Study location
NCT00457847: Recruiting study of Lung Transplantation and Primary Graft Dysfunction, sponsored by University of Pennsylvania.
NCT00457847 is a study of Lung Transplantation and Primary Graft Dysfunction that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 1,150 participants, above the 240-participant average among 12 other Lung Transplantation trials with a reported enrollment target (379% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00457847, a study of Lung Transplantation and Primary Graft Dysfunction, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- 1,150 participants
- Enrollment target
- 1
- Study location
Study Summary
Primary graft dysfunction (PGD) is a severe lung injury that can occur in the days following lung transplant surgery. The purpose of this study is to identify genetic factors that may put someone at risk for developing PGD.
Primary Outcome
ISHLT standard definition and grading system will be used
Conditions Studied
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,150 participants |
| Start Date | 2007-02 |
| Est. Completion | 2026-06 |
What NCT00457847 shows while recruiting
NCT00457847 is an observational study that tracks outcomes without assigning an intervention. Its 1,150 participants enrollment target places it among the larger protocols in the corpus, above the 240-participant average among 12 other Lung Transplantation trials with a reported enrollment target (379% higher).
The record links to 2 conditions, with Lung Transplantation appearing as the primary indexed condition, and to 0 interventions.
NCT00457847 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00457847 about?
NCT00457847 is a clinical study titled "Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation". Primary graft dysfunction (PGD) is a severe lung injury that can occur in the days following lung transplant surgery. The purpose of this study is to identify genetic factors that may put someone at risk for developing PGD.
What is the current status of trial NCT00457847?
This trial is currently recruiting. The enrollment target is 1,150 participants. The study started on 2007-02. Estimated completion is 2026-06.
What conditions does trial NCT00457847 study?
This clinical trial studies the following conditions: Lung Transplantation, Primary Graft Dysfunction.
Who is sponsoring clinical trial NCT00457847?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00457847 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lung Transplantation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00457847's enrollment target sits among peer trials
1,150 1st of 12 the highest of 12 other Lung Transplantation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lung Transplantation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome.
RECRUITING · Phase 2
-
Trifecta-Lung cfDNA-MMDx Study
RECRUITING
-
Risk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation
RECRUITING
-
Transplanting Lungs From Uncontrolled Donation After Circulatory Death
RECRUITING · NA
-
This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft Dysfunction
RECRUITING · Phase 2
-
OCS™ Lung TOP Registry For Donor Lungs for Transplantation
ACTIVE NOT RECRUITING
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