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NCT00454285 · ClinicalTrials.gov registry record · Phase 2
Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing
A Phase 2 study, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- Phase 2
- Development phase
- 290
- Enrollment target
NCT00454285: Completed Phase 2 study, sponsored by Wake Forest University Health Sciences.
NCT00454285 is a Phase 2 study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 290 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (118% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00454285, a Phase 2 study, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 290 participants
- Enrollment target
Study Summary
The major purposes of this prospective, randomized, clinical study are to: 1. Determine and compare the true incidence, nature, magnitude, and duration (INMD) of bacteremia (bacteria found in the bloodstream) resulting from a highly invasive dental office procedure (tooth extraction) and a minimally invasive and naturally occurring source of bacteremia (tooth brushing); 2. Measure the effect of the American Heart Association's guidelines for amoxicillin prophylaxis (preventive treatment) on the INMD of bacteremia resulting from a single tooth extraction.
Interventions
- DRUG Effect of Amoxicillin on bacteremia following a single-tooth extraction
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 290 participants |
| Start Date | 2003-01 |
| Est. Completion | 2006-06 |
| Phase | Phase 2 |
What the finished NCT00454285 record still lists
NCT00454285 is an interventional study that assigns participants to a tested intervention. The registered 290 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (118% higher).
The record links to 0 conditions, and to 1 intervention - of which Effect of Amoxicillin on bacteremia following a single-tooth extraction is the first listed.
NCT00454285 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00454285 about?
NCT00454285 is a clinical study titled "Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing". The major purposes of this prospective, randomized, clinical study are to: 1. Determine and compare the true incidence, nature, magnitude, and duration (INMD) of bacteremia (bacteria found in the bloodstream) resulting from a highly invasive dental office procedure (tooth extraction) and a minimall...
What is the current status of trial NCT00454285?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 290 participants. The study started on 2003-01. Estimated completion is 2006-06.
What interventions are being tested in trial NCT00454285?
The interventions under investigation include: Effect of Amoxicillin on bacteremia following a single-tooth extraction (DRUG).
Who is sponsoring clinical trial NCT00454285?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00454285's enrollment target sits among peer trials
290 191st of 2000 higher than 1,810 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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