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NCT00449163 · ClinicalTrials.gov registry record · Phase 2
Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer
A Phase 2 study, sponsored by University of Miami.
- Terminated
- Registry status
- Phase 2
- Development phase
- 25
- Enrollment target
NCT00449163 is a Phase 2 study that was terminated before completion, run by University of Miami. The registered enrollment target is 25 participants.
The verdict
NCT00449163, a Phase 2 study, was terminated before completion, sponsored by University of Miami.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 25 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy, such as irinotecan, floxuridine, and leucovorin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of colorectal cancer by blocking blood flow to the tumor. Giving combination chemotherapy together with bevacizumab may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving combination chemotherapy together with bevacizumab works in treating patients with stage IV colorectal cancer.
Interventions
- DRUG Leucovorin
- DRUG Irinotecan
- BIOLOGICAL Bevacizumab
- DRUG Floxuridine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2006-03-01 |
| Est. Completion | 2010-03 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00449163
The ClinicalTrials.gov registry entry for NCT00449163 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Leucovorin is the first listed.
NCT00449163 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00449163 about?
NCT00449163 is a clinical study titled "Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer". RATIONALE: Drugs used in chemotherapy, such as irinotecan, floxuridine, and leucovorin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some ...
What is the current status of trial NCT00449163?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2006-03-01. Estimated completion is 2010-03.
What interventions are being tested in trial NCT00449163?
The interventions under investigation include: Leucovorin (DRUG), Irinotecan (DRUG), Bevacizumab (BIOLOGICAL), Floxuridine (DRUG).
Who is sponsoring clinical trial NCT00449163?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
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