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NCT00442052 · ClinicalTrials.gov registry record · Phase 1
To Compare the Gastroprotective Effects and Pharmacokinetic Profile of PA Versus Enteric-Coated Aspirin
A Phase 1 study, sponsored by POZEN.
- Completed
- Registry status
- Phase 1
- Development phase
- 80
- Enrollment target
NCT00442052: Completed Phase 1 study, sponsored by POZEN.
NCT00442052 is a Phase 1 study that has completed, run by POZEN. The registered enrollment target is 80 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00442052, a Phase 1 study, has completed, sponsored by POZEN.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 80 participants
- Enrollment target
Study Summary
Primary: To compare the gastroprotective effects of a once-daily dose of PA 325 combination tablet combining 325 mg pH sensitive aspirin and 20 mg immediate release omeprazole versus a once-daily dose of 325 mg enteric coated aspirin utilizing Lanza scores from endoscopy findings in normal healthy volunteers.
Interventions
- DRUG aspirin
- DRUG omeprazole
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2006-11 |
| Est. Completion | 2007-01 |
| Phase | Phase 1 |
What the finished NCT00442052 record still lists
NCT00442052 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher).
The record links to 0 conditions, and to 2 interventions - of which aspirin is the first listed.
NCT00442052 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00442052 about?
NCT00442052 is a clinical study titled "To Compare the Gastroprotective Effects and Pharmacokinetic Profile of PA Versus Enteric-Coated Aspirin". Primary: To compare the gastroprotective effects of a once-daily dose of PA 325 combination tablet combining 325 mg pH sensitive aspirin and 20 mg immediate release omeprazole versus a once-daily dose of 325 mg enteric coated aspirin utilizing Lanza scores from endoscopy findings in normal healthy v...
What is the current status of trial NCT00442052?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2006-11. Estimated completion is 2007-01.
What interventions are being tested in trial NCT00442052?
The interventions under investigation include: aspirin (DRUG), omeprazole (DRUG).
Who is sponsoring clinical trial NCT00442052?
This trial is sponsored by POZEN, which has 24 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00442052's enrollment target sits among peer trials
80 672nd of 2000 higher than 1,305 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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